Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O94832 | MYO1D; KIAA0727 | Unconventional myosin-Id | Homo sapiens (Human) | 1006 aa |
Protein Details: O94832 (MYO1D)
Protein Information
| Accession | O94832 |
|---|---|
| Protein Names | Unconventional myosin-Id |
| Gene Symbol | MYO1D; KIAA0727 |
| Organism | Homo sapiens (Human) |
| Length | 1006 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.837
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.837
36/46 (78.3%)
4
PC3 cells
Specificity: 0.093
4/4 (100.0%)
3
Cerebral cortex
Specificity: 0.070
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAEQESLEFG11KADFVLMDTV21SMPEFMANLR31LRFEKGRIYT41FIGEVVVSVN
51-10051PYKLLNIYGR61DTIEQYKGRE71LYERPPHLFA81IADAAYKAMK91RRSKDTCIVI
101-150101SGESGAGKTE111ASKYIMQYIA121AITNPSQRAE131VERVKNMLLK141SNCVLEAFGN
151-200151AKTNRNDNSS161RFGKYMDINF171DFKGDPIGGH181INNYLLEKSR191VIVQQPGERS
201-250201FHSFYQLLQG211GSEQMLRSLH221LQKSLSSYNY231IHVGAQLKSS241INDAAEFRVV
251-300251ADAMKVIGFK261PEEIQTVYKI271LAAILHLGNL281KFVVDGDTPL291IENGKVVSII
301-350301AELLSTKTDM311VEKALLYRTV321ATGRDIIDKQ331HTEQEASYGR341DAFAKAIYER
351-400351LFCWIVTRIN361DIIEVKNYDT371TIHGKNTVIG381VLDIYGFEIF391DNNSFEQFCI
401-450401NYCNEKLQQL411FIQLVLKQEQ421EEYQREGIPW431KHIDYFNNQI441IVDLVEQQHK
451-500451GIIAILDDAC461MNVGKVTDEM471FLEALNSKLG481KHAHFSSRKL491CASDKILEFD
501-550501RDFRIRHYAG511DVVYSVIGFI521DKNKDTLFQD531FKRLMYNSSN541PVLKNMWPEG
551-600551KLSITEVTKR561PLTAATLFKN571SMIALVDNLA581SKEPYYVRCI591KPNDKKSPQI
601-650601FDDERCRHQV611EYLGLLENVR621VRRAGFAFRQ631TYEKFLHRYK641MISEFTWPNH
651-700651DLPSDKEAVK661KLIERCGFQD671DVAYGKTKIF681IRTPRTLFTL691EELRAQMLIR
701-750701IVLFLQKVWR711GTLARMRYKR721TKAALTIIRY731YRRYKVKSYI741HEVARRFHGV
751-800751KTMRDYGKHV761KWPSPPKVLR771RFEEALQTIF781NRWRASQLIK791SIPASDLPQV
801-850801RAKVAAVEML811KGQRADLGLQ821RAWEGNYLAS831KPDTPQTSGT841FVPVANELKR
851-900851KDKYMNVLFS861CHVRKVNRFS871KVEDRAIFVT881DRHLYKMDPT891KQYKVMKTIP
901-950901LYNLTGLSVS911NGKDQLVVFH921TKDNKDLIVC931LFSKQPTHES941RIGELVGVLV
951-1000951NHFKSEKRHL961QVNVTNPVQC971SLHGKKCTVS981VETRLNQPQP991DFTKNRSGFI
1001-10061001LSVPGN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 97 | Prediction (Low) | - | - |
| 143 | Prediction (High) | - | - |
| 353 | Prediction (High) | - | - |
| 460 | Prediction (Low) | - | - |
| 491 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | Myosin head (motor domain) | - |
| 589 | Prediction (Low) | - | - |
| 861 | Prediction (High) | - | - |
| 930 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 148 | F → _G149insPKASNCVLEAF | 0.002141 | INS | In Frame Ins | SKCM |
| 350 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 588 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 588 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 605 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 622 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 622 | R → C | 0.004577 | SNP | Missense Mutation | STAD |
| 622 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 622 | R → C | 0.006993 | SNP | Missense Mutation | LAML |
| 622 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 629 | R → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 770 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 864 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 882 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |