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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O95136 S1PR2; EDG5 Sphingosine 1-phosphate receptor 2 (S1P … Homo sapiens (Human) 353 aa

Protein Details: O95136 (S1PR2)

Protein Information
Accession O95136
Protein Names Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5)
Gene Symbol S1PR2; EDG5
Organism Homo sapiens (Human)
Length 353 aa
Isoforms No isoforms
Related PMIDs 29575903 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 1.000
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGSLYSEYLN11PNKVQEHYNY21TKETLETQET31TSRQVASAFI41VILCCAIVVE
51-10051NLLVLIAVAR61NSKFHSAMYL71FLGNLAASDL81LAGVAFVANT91LLSGSVTLRL
101-150101TPVQWFAREG111SAFITLSASV121FSLLAIAIER131HVAIAKVKLY141GSDKSCRMLL
151-200151LIGASWLISL161VLGGLPILGW171NCLGHLEACS181TVLPLYAKHY191VLCVVTIFSI
201-250201ILLAIVALYV211RIYCVVRSSH221ADMAAPQTLA231LLKTVTIVLG241VFIVCWLPAF
251-300251SILLLDYACP261VHSCPILYKA271HYFFAVSTLN281SLLNPVIYTW291RSRDLRREVL
301-350301RPLQCWRPGV311GVQGRRRGGT321PGHHLLPLRS331SSSLERGMHM341PTSPTFLEGN
351-353351TVV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
44 Prediction (Low) - -
146 Prediction (Medium) - -
214 Prediction (Low) - -
259 Prediction (Low) - -
305 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
45 C → C 0.002545 SNP Silent GBM
141 G → C 0.002033 SNP Missense Mutation LUSC
312 V → Cfs*83 0.002288 DEL Frame Shift Del STAD