Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95136 | S1PR2 | Sphingosine 1-phosphate receptor 2 (S1P … | Homo sapiens (Human) | 353 aa |
Protein Details: O95136 (S1PR2)
Protein Information
| Accession | O95136 |
|---|---|
| Protein Names | Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5) |
| Gene Symbol | S1PR2 |
| Organism | Homo sapiens (Human) |
| Length | 353 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGSLYSEYLN11PNKVQEHYNY21TKETLETQET31TSRQVASAFI41VILCCAIVVE
51-10051NLLVLIAVAR61NSKFHSAMYL71FLGNLAASDL81LAGVAFVANT91LLSGSVTLRL
101-150101TPVQWFAREG111SAFITLSASV121FSLLAIAIER131HVAIAKVKLY141GSDKSCRMLL
151-200151LIGASWLISL161VLGGLPILGW171NCLGHLEACS181TVLPLYAKHY191VLCVVTIFSI
201-250201ILLAIVALYV211RIYCVVRSSH221ADMAAPQTLA231LLKTVTIVLG241VFIVCWLPAF
251-300251SILLLDYACP261VHSCPILYKA271HYFFAVSTLN281SLLNPVIYTW291RSRDLRREVL
301-350301RPLQCWRPGV311GVQGRRRGGT321PGHHLLPLRS331SSSLERGMHM341PTSPTFLEGN
351-353351TVV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 44 | Family A G protein-coupled receptor-like | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.89
|
|
| 45 | Family A G protein-coupled receptor-like | - | - |
Deep-Palm: 0.91
|
|
| 146 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.96
|
|
| 172 | - | - | - |
Deep-Palm: 0.98
|
|
| 179 | - | - | - |
Deep-Palm: 0.82
|
|
| 193 | - | - | - |
Deep-Palm: 0.71
|
|
| 214 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.91
|
|
| 245 | - | - | - |
Deep-Palm: 0.69
|
|
| 259 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.41
|
|
| 264 | - | - | - |
Deep-Palm: 0.72
|
|
| 305 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
PC3
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 45 | C → C | 0.002545 | SNP | Silent | GBM |
| 141 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 312 | V → Cfs*83 | 0.002288 | DEL | Frame Shift Del | STAD |