Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O95336 PGLS 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31) Homo sapiens (Human) 258 aa

Protein Details: O95336 (PGLS)

Protein Information
Accession O95336
Protein Names 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)
Gene Symbol PGLS
Organism Homo sapiens (Human)
Length 258 aa
Isoforms No isoforms
Related PMIDs 29733200 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
293T cells
Specificity: 0.571
4/10 (40.0%)
3
PC3 cells
Specificity: 0.429
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAPAPGLIS11VFSSSQELGA21ALAQLVAQRA31ACCLAGARAR41FALGLSGGSL
51-10051VSMLARELPA61AVAPAGPASL71ARWTLGFCDE81RLVPFDHAES91TYGLYRTHLL
101-150101SRLPIPESQV111ITINPELPVE121EAAEDYAKKL131RQAFQGDSIP141VFDLLILGVG
151-200151PDGHTCSLFP161DHPLLQEREK171IVAPISDSPK181PPPQRVTLTL191PVLNAARTVI
201-250201FVATGEGKAA211VLKRILEDQE221ENPLPAALVQ231PHTGKLCWFL241DEAAARLLTV
251-258251PFEKHSTL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
32 Prediction (High) - -
33 Prediction (High) - -
78 Prediction (Low) - -
237 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
69 S → C 0.002506 SNP Missense Mutation COAD
101 S → C 0.002033 SNP Missense Mutation LUSC
153 G → C 0.001887 SNP Missense Mutation UCEC
185 R → C 0.001887 SNP Missense Mutation UCEC
214 R → C 0.007299 SNP Missense Mutation READ