Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95372 | LYPLA2 | Acyl-protein thioesterase 2 (APT-2) (EC … | Homo sapiens (Human) | 231 aa |
Protein Details: O95372 (LYPLA2)
Protein Information
| Accession | O95372 |
|---|---|
| Protein Names | Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase II) (LPL-II) (LysoPLA II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) |
| Gene Symbol | LYPLA2 |
| Organism | Homo sapiens (Human) |
| Length | 231 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MCGNTMSVPL11LTDAATVSGA21ERETAAVIFL31HGLGDTGHSW41ADALSTIRLP
51-10051HVKYICPHAP61RIPVTLNMKM71VMPSWFDLMG81LSPDAPEDEA91GIKKAAENIK
101-150101ALIEHEMKNG111IPANRIVLGG121FSQGGALSLY131TALTCPHPLA141GIVALSCWLP
151-200151LHRAFPQAAN161GSAKDLAILQ171CHGELDPMVP181VRFGALTAEK191LRSVVTPARV
201-231201QFKTYPGVMH211SSCPQEMAAV221KEFLEKLLPP231V
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 2 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
| 56 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.66
|
|
| 135 | - | - | - |
Deep-Palm: 0.94
|
|
| 147 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.96
|
|
| 171 | - | - | - |
Deep-Palm: 0.89
|
|
| 213 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
293T cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.