Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
O95498 VNN2 Pantetheine hydrolase VNN2 (EC 3.5.1.92) … Homo sapiens (Human) 520 aa

Protein Details: O95498 (VNN2)

Protein Information
AccessionO95498
Protein NamesPantetheine hydrolase VNN2 (EC 3.5.1.92) (Glycosylphosphatidyl inositol-anchored protein GPI-80) (Protein FOAP-4) (Vascular non-inflammatory molecule 2) (Vanin-2)
Gene SymbolVNN2
OrganismHomo sapiens (Human)
Length520 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVTSSFPISV11AVFALITLQV21GTQDSFIAAV31YEHAVILPNK41TETPVSQEDA
51-10051LNLMNENIDI61LETAIKQAAE71QGARIIVTPE81DALYGWKFTR91ETVFPYLEDI
101-150101PDPQVNWIPC111QDPHRFGHTP121VQARLSCLAK131DNSIYVLANL141GDKKPCNSRD
151-200151STCPPNGYFQ161YNTNVVYNTE171GKLVARYHKY181HLYSEPQFNV191PEKPELVTFN
201-250201TAFGRFGIFT211CFDIFFYDPG221VTLVKDFHVD231TILFPTAWMN241VLPLLTAIEF
251-300251HSAWAMGMGV261NLLVANTHHV271SLNMTGSGIY281APNGPKVYHY291DMKTELGKLL
301-350301LSEVDSHPLS311SLAYPTAVNW321NAYATTIKPF331PVQKNTFRGF341ISRDGFNFTE
351-400351LFENAGNLTV361CQKELCCHLS371YRMLQKEENE381VYVLGAFTGL391HGRRRREYWQ
401-450401VCTLLKCKTT411NLTTCGRPVE421TASTRFEMFS431LSGTFGTEYV441FPEVLLTEIH
451-500451LSPGKFEVLK461DGRLVNKNGS471SGPILTVSLF481GRWYTKDSLY491SSCGTSNSAI
501-520501TYLLIFILLM511IIALQNIVML
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
110 - - -
Deep-Palm: 0.19
127 - - -
GPS-Palm: 0.76
Deep-Palm: 0.85
146 - - -
Deep-Palm: 0.13
153 - - -
Deep-Palm: 0.03
211 - - -
Deep-Palm: 0.61
361 SWISSPALM DBPTM CYSMODDB Vanin C-terminal domain - -
GPS-Palm: 0.86
Deep-Palm: 0.57
366 SWISSPALM DBPTM CYSMODDB Vanin C-terminal domain - -
GPS-Palm: 0.72
Deep-Palm: 0.75
367 SWISSPALM DBPTM CYSMODDB Vanin C-terminal domain - -
GPS-Palm: 0.69
Deep-Palm: 0.56
402 - - -
GPS-Palm: 0.86
Deep-Palm: 0.87
407 - - -
GPS-Palm: 0.74
Deep-Palm: 0.85
415 - - -
GPS-Palm: 0.89
Deep-Palm: 0.81
493 - - -
Deep-Palm: 0.84
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
146 C → C 0.001887 SNP Silent UCEC
149 R → C 0.002141 SNP Missense Mutation SKCM
153 C → C 0.002506 SNP Silent COAD
366 C → C 0.002427 SNP Silent BLCA
366 C → C 0.005435 SNP Silent ESCA
402 C → C 0.001887 SNP Silent UCEC
432 S → C 0.001764 SNP Missense Mutation LUAD
484 Y → C 0.002294 SNP Missense Mutation OV