Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95500 | CLDN14 | Claudin-14 | Homo sapiens (Human) | 239 aa |
Protein Details: O95500 (CLDN14)
Protein Information
| Accession | O95500 |
|---|---|
| Protein Names | Claudin-14 |
| Gene Symbol | CLDN14 |
| Organism | Homo sapiens (Human) |
| Length | 239 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASTAVQLLG11FLLSFLGMVG21TLITTILPHW31RRTAHVGTNI41LTAVSYLKGL
51-10051WMECVWHSTG61IYQCQIYRSL71LALPQDLQAA81RALMVISCLL91SGIACACAVI
101-150101GMKCTRCAKG111TPAKTTFAIL121GGTLFILAGL131LCMVAVSWTT141NDVVQNFYNP
151-200151LLPSGMKFEI161GQALYLGFIS171SSLSLIGGTL181LCLSCQDEAP191YRPYQAPPRA
201-239201TTTTANTAPA211YQPPAAYKDN221RAPSVTSATH231SGYRLNDYV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 54 | - | - | - |
Deep-Palm: 0.04
|
|
| 64 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.16
|
|
| 88 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.88
|
|
| 95 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.93
|
|
| 97 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.94
|
|
| 104 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.81
|
| 107 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.79
|
| 132 | - | - | - |
Deep-Palm: 0.93
|
|
| 182 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.98
|
| 185 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
PC3
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 88 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 95 | C → C | 0.006944 | SNP | Silent | TGCT |
| 95 | C → C | 0.001887 | SNP | Silent | UCEC |
| 121 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 138 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |