Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95500 | CLDN14; UNQ777/PRO1571 | Claudin-14 | Homo sapiens (Human) | 239 aa |
Protein Details: O95500 (CLDN14)
Protein Information
| Accession | O95500 |
|---|---|
| Protein Names | Claudin-14 |
| Gene Symbol | CLDN14; UNQ777/PRO1571 |
| Organism | Homo sapiens (Human) |
| Length | 239 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 1.000
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASTAVQLLG11FLLSFLGMVG21TLITTILPHW31RRTAHVGTNI41LTAVSYLKGL
51-10051WMECVWHSTG61IYQCQIYRSL71LALPQDLQAA81RALMVISCLL91SGIACACAVI
101-150101GMKCTRCAKG111TPAKTTFAIL121GGTLFILAGL131LCMVAVSWTT141NDVVQNFYNP
151-200151LLPSGMKFEI161GQALYLGFIS171SSLSLIGGTL181LCLSCQDEAP191YRPYQAPPRA
201-239201TTTTANTAPA211YQPPAAYKDN221RAPSVTSATH231SGYRLNDYV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 64 | Prediction (Medium) | - | - |
| 88 | Prediction (Medium) | - | - |
| 95 | Prediction (Low) | - | - |
| 97 | Prediction (Medium) | - | - |
| 104 | DBPTM SWISSPALM Prediction (Medium) | - | - |
| 107 | DBPTM SWISSPALM Prediction (Low) | - | - |
| 182 | DBPTM SWISSPALM Prediction (Low) | - | - |
| 185 | DBPTM SWISSPALM Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 88 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 95 | C → C | 0.006944 | SNP | Silent | TGCT |
| 95 | C → C | 0.001887 | SNP | Silent | UCEC |
| 121 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 138 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |