Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95807 | TMEM50A; SMP1; UNQ386/PRO718 | Transmembrane protein 50A (Small membrane … | Homo sapiens (Human) | 157 aa |
Protein Details: O95807 (TMEM50A)
Protein Information
| Accession | O95807 |
|---|---|
| Protein Names | Transmembrane protein 50A (Small membrane protein 1) |
| Gene Symbol | TMEM50A; SMP1; UNQ386/PRO718 |
| Organism | Homo sapiens (Human) |
| Length | 157 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 29575903 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.860
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
43
LNCaP cells
Specificity: 0.860
43/46 (93.5%)
3
PC3 cells
Specificity: 0.060
3/4 (75.0%)
2
DU145 cells
Specificity: 0.040
2/2 (100.0%)
2
Cerebral cortex
Specificity: 0.040
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSGFLEGLRC11SECIDWGEKR21NTIASIAAGV31LFFTGWWIII41DAAVIYPTMK
51-10051DFNHSYHACG61VIATIAFLMI71NAVSNGQVRG81DSYSEGCLGQ91TGARIWLFVG
101-150101FMLAFGSLIA111SMWILFGGYV121AKEKDIVYPG131IAVFFQNAFI141FFGGLVFKFG
151-157151RTEDLWQ
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 10 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | 29575903 |
| 13 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Uncharacterised protein family (UPF0220) | 29575903 |
| 87 | Experimental Prediction (Medium) | Uncharacterised protein family (UPF0220) | 29575903 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 20 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 83 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 89 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |