Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95837 | GNA14 | Guanine nucleotide-binding protein subunit alpha-14 … | Homo sapiens (Human) | 355 aa |
Protein Details: O95837 (GNA14)
Protein Information
| Accession | O95837 |
|---|---|
| Protein Names | Guanine nucleotide-binding protein subunit alpha-14 (G alpha-14) (G-protein subunit alpha-14) |
| Gene Symbol | GNA14 |
| Organism | Homo sapiens (Human) |
| Length | 355 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29575903 32944167 33636221 |
| Database Sources | dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.571
4/4 (100.0%)
1
HeLa cells
Specificity: 0.143
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.143
1/2 (50.0%)
1
Liver membrane
Specificity: 0.143
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAGCCCLSAE11EKESQRISAE21IERQLRRDKK31DARRELKLLL41LGTGESGKST
51-10051FIKQMRIIHG61SGYSDEDRKG71FTKLVYQNIF81TAMQAMIRAM91DTLRIQYVCE
101-150101QNKENAQIIR111EVEVDKVSML121SREQVEAIKQ131LWQDPGIQEC141YDRRREYQLS
151-200151DSAKYYLTDI161DRIATPSFVP171TQQDVLRVRV181PTTGIIEYPF191DLENIIFRMV
201-250201DVGGQRSERR211KWIHCFESVT221SIIFLVALSE231YDQVLAECDN241ENRMEESKAL
251-300251FKTIITYPWF261LNSSVILFLN271KKDLLEEKIM281YSHLISYFPE291YTGPKQDVRA
301-350301ARDFILKLYQ311DQNPDKEKVI321YSHFTCATDT331DNIRFVFAAV341KDTILQLNLR
351-355351EFNLV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 4 | DBPTM SWISSPALM Prediction (High) | - | - |
| 5 | DBPTM SWISSPALM Prediction (High) | - | - |
| 6 | DBPTM SWISSPALM Prediction (High) | - | - |
| 140 | Prediction (Low) | - | - |
| 215 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 132 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 140 | C → C | 0.002288 | SNP | Silent | STAD |
| 162 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 177 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 243 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 334 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |