Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95857 | TSPAN13 | Tetraspanin-13 (Tspan-13) (Tetraspan NET-6) (Transmembrane … | Homo sapiens (Human) | 204 aa |
Protein Details: O95857 (TSPAN13)
Protein Information
| Accession | O95857 |
|---|---|
| Protein Names | Tetraspanin-13 (Tspan-13) (Tetraspan NET-6) (Transmembrane 4 superfamily member 13) |
| Gene Symbol | TSPAN13 |
| Organism | Homo sapiens (Human) |
| Length | 204 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVCGGFACSK11NCLCALNLLY21TLVSLLLIGI31AAWGIGFGLI41SSLRVVGVVI
51-10051AVGIFLFLIA61LVGLIGAVKH71HQVLLFFYMI81ILLLVFIVQF91SVSCACLALN
101-150101QEQQGQLLEV111GWNNTASARN121DIQRNLNCCG131FRSVNPNDTC141LASCVKSDHS
151-200151CSPCAPIIGE161YAGEVLRFVG171GIGLFFSFTE181ILGVWLTYRY191RNQKDPRANP
201-204201SAFL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
| 8 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.02
|
| 12 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.14
|
|
| 14 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.96
|
|
| 94 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.68
|
|
| 96 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.81
|
|
| 128 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.87
Deep-Palm: 0.81
|
|
| 129 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.76
|
|
| 140 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.06
|
|
| 144 | - | - | - |
Deep-Palm: 0.16
|
|
| 151 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.38
|
|
| 154 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.74
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
LNCaP
Specificity: 0.667
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP cells (Mass)
Specificity: 0.333
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 140 | C → F | 0.002545 | SNP | Missense Mutation | GBM |