Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| O95858 | TSPAN15 | Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane … | Homo sapiens (Human) | 294 aa |
Protein Details: O95858 (TSPAN15)
Protein Information
| Accession | O95858 |
|---|---|
| Protein Names | Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15) |
| Gene Symbol | TSPAN15 |
| Organism | Homo sapiens (Human) |
| Length | 294 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 32944167 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPRGDSEQVR11YCARFSYLWL21KFSLIIYSTV31FWLIGALVLS41VGIYAEVERQ
51-10051KYKTLESAFL61APAIILILLG71VVMFMVSFIG81VLASLRDNLY91LLQAFMYILG
101-150101ICLIMELIGG111VVALTFRNQT121IDFLNDNIRR131GIENYYDDLD141FKNIMDFVQK
151-200151KFKCCGGEDY161RDWSKNQYHD171CSAPGPLACG181VPYTCCIRNT191TEVVNTMCGY
201-250201KTIDKERFSV211QDVIYVRGCT221NAVIIWFMDN231YTIMAGILLG241ILLPQFLGVL
251-294251LTLLYITRVE261DIIMEHSVTD271GLLGPGAKPS281VEAAGTGCCL291CYPN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 12 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.06
|
|
| 102 | - | - | - |
Deep-Palm: 0.46
|
|
| 154 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.83
Deep-Palm: 0.58
|
|
| 155 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.91
Deep-Palm: 0.48
|
|
| 171 | - | - | - |
Deep-Palm: 0.12
|
|
| 179 | - | - | - |
Deep-Palm: 0.16
|
|
| 185 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.13
|
|
| 186 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.28
|
|
| 198 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.12
|
|
| 219 | - | - | - |
Deep-Palm: 0.37
|
|
| 288 | SWISSPALM | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.88
Deep-Palm: 0.04
|
| 289 | SWISSPALM | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.94
Deep-Palm: 0.04
|
| 291 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.97
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
4
LNCaP
Specificity: 0.222
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.222
4/4 (100.0%)
3
PC3
Specificity: 0.167
3/3 (100.0%)
2
Jurkat T cell
Specificity: 0.111
2/2 (100.0%)
1
heart
Specificity: 0.056
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Cerebral Cortex (Mass)
Specificity: 0.167
3/4 (75.0%)
1
LNCaP cells (Mass)
Specificity: 0.056
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 110 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 136 | Y → C | 0.002294 | SNP | Missense Mutation | OV |