Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P00325-2 | ADH1B | All-trans-retinol dehydrogenase [NAD(+)] ADH1B (EC … | Homo sapiens (Human) | 335 aa |
Protein Details: P00325-2 (ADH1B)
Protein Information
| Accession | P00325-2 |
|---|---|
| Protein Names | All-trans-retinol dehydrogenase [NAD(+)] ADH1B (EC 1.1.1.105) (Alcohol dehydrogenase 1B) (Alcohol dehydrogenase subunit beta) |
| Gene Symbol | ADH1B |
| Organism | Homo sapiens (Human) |
| Length | 335 aa |
| Isoforms | |
| Related PMIDs | 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVAVGICHTD11DHVVSGNLVT21PLPVILGHEA31AGIVESVGEG41VTTVKPGDKV
51-10051IPLFTPQCGK61CRVCKNPESN71YCLKNDLGNP81RGTLQDGTRR91FTCRGKPIHH
101-150101FLGTSTFSQY111TVVDENAVAK121IDAASPLEKV131CLIGCGFSTG141YGSAVNVAKV
151-200151TPGSTCAVFG161LGGVGLSAVM171GCKAAGAARI181IAVDINKDKF191AKAKELGATE
201-250201CINPQDYKKP211IQEVLKEMTD221GGVDFSFEVI231GRLDTMMASL241LCCHEACGTS
251-300251VIVGVPPASQ261NLSINPMLLL271TGRTWKGAVY281GGFKSKEGIP291KLVADFMAKK
301-335301FSLDALITHV311LPFEKINEGF321DLLHSGKSIR331TVLTF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | - | - | - |
Deep-Palm: 0.09
|
|
| 47 | - | - | - |
Deep-Palm: 0.84
|
|
| 58 | - | - | - |
GPS-Palm: 0.93
|
|
| 98 | - | - | - |
Deep-Palm: 0.85
|
|
| 101 | - | - | - |
Deep-Palm: 0.32
|
|
| 104 | - | - | - |
Deep-Palm: 0.18
|
|
| 112 | - | - | - |
Deep-Palm: 0.52
|
|
| 133 | - | - | - |
Deep-Palm: 0.80
|
|
| 171 | - | - | - |
Deep-Palm: 0.96
|
|
| 172 | - | - | - |
GPS-Palm: 0.91
|
|
| 175 | - | - | - |
Deep-Palm: 0.96
|
|
| 196 | - | - | - |
Deep-Palm: 0.97
|
|
| 212 | - | - | - |
Deep-Palm: 0.97
|
|
| 241 | - | - | - |
Deep-Palm: 0.97
|
|
| 282 | - | - | - |
Deep-Palm: 0.74
|
|
| 283 | - | - | - |
Deep-Palm: 0.86
|
|
| 287 | - | - | - |
Deep-Palm: 0.71
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 38 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 112 | C → C | 0.002288 | SNP | Silent | STAD |
| 183 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 193 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |