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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P00342 Ldhc L-lactate dehydrogenase C chain (LDH-C) … Mus musculus (Mouse) 332 aa

Protein Details: P00342 (Ldhc)

Protein Information
AccessionP00342
Protein NamesL-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (LDH testis subunit) (LDH-X)
Gene SymbolLdhc
OrganismMus musculus (Mouse)
Length332 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSTVKEQLIQ11NLVPEDKLSR21CKITVVGVGN31VGMACAISIL41LKGLADELAL
51-10051VDADTNKLRG61EALDLLHGSL71FLSTPKIVFG81KDYNVSANSK91LVIITAGARM
101-150101VSGETRLDLL111QRNVAIMKAI121VPGIVQNSPD131CKIIIVTNPV141DILTYVVWKI
151-200151SGFPVGRVIG161SGCNLDSARF171RYLIGEKLGV181NPTSCHGWVL191GEHGDSSVPI
201-250201WSGVNVAGVT211LKSLNPAIGT221DSDKEHWKNV231HKQVVEGGYE241VLNMKGYTSW
251-300251AIGLSVTDLA261RSILKNLKRV271HPVTTLVKGF281HGIKEEVFLS291IPCVLGQSGI
301-332301TDFVKVNMTA311EEEGLLKKSA321DTLWNMQKDL331QL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
21 NAD(P)-binding domain superfamily Prokaryotic membrane lipoprotein lipid attachment site profile. L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) - -
Deep-Palm: 0.89
35 L-lactate/malate dehydrogenase L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) NAD(P)-binding domain superfamily Lactate/malate dehydrogenase, N-terminal - -
GPS-Palm: 0.82
Deep-Palm: 0.97
131 - - -
Deep-Palm: 0.77
163 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (34200797)
Liver (37925639)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.95
Deep-Palm: 0.95
185 - - -
Deep-Palm: 0.95
293 - - -
GPS-Palm: 0.77
Deep-Palm: 0.90
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
Brain
Specificity: 0.286
2/2 (100.0%)
2
Testis
Specificity: 0.286
2/2 (100.0%)
1
Liver
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver tissue (Mass)
Specificity: 0.286
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine