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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P00352 ALDH1A1; ALDC; ALDH1; PUMB1 Aldehyde dehydrogenase 1A1 (EC 1.2.1.19) … Homo sapiens (Human) 501 aa

Protein Details: P00352 (ALDH1A1)

Protein Information
Accession P00352
Protein Names Aldehyde dehydrogenase 1A1 (EC 1.2.1.19) (EC 1.2.1.28) (EC 1.2.1.3) (EC 1.2.1.36) (3-deoxyglucosone dehydrogenase) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (Retinal dehydrogenase 1) (RALDH 1) (RalDH1)
Gene Symbol ALDH1A1; ALDC; ALDH1; PUMB1
Organism Homo sapiens (Human)
Length 501 aa
Isoforms No isoforms
Related PMIDs 31251020 33636221 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.643
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
9
LNCaP cells
Specificity: 0.643
9/46 (19.6%)
4
Cerebral cortex
Specificity: 0.286
4/4 (100.0%)
1
Liver membrane
Specificity: 0.071
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSSSGTPDLP11VLLTDLKIQY21TKIFINNEWH31DSVSGKKFPV41FNPATEEELC
51-10051QVEEGDKEDV61DKAVKAARQA71FQIGSPWRTM81DASERGRLLY91KLADLIERDR
101-150101LLLATMESMN111GGKLYSNAYL121NDLAGCIKTL131RYCAGWADKI141QGRTIPIDGN
151-200151FFTYTRHEPI161GVCGQIIPWN171FPLVMLIWKI181GPALSCGNTV191VVKPAEQTPL
201-250201TALHVASLIK211EAGFPPGVVN221IVPGYGPTAG231AAISSHMDID241KVAFTGSTEV
251-300251GKLIKEAAGK261SNLKRVTLEL271GGKSPCIVLA281DADLDNAVEF291AHHGVFYHQG
301-350301QCCIAASRIF311VEESIYDEFV321RRSVERAKKY331ILGNPLTPGV341TQGPQIDKEQ
351-400351YDKILDLIES361GKKEGAKLEC371GGGPWGNKGY381FVQPTVFSNV391TDEMRIAKEE
401-450401IFGPVQQIMK411FKSLDDVIKR421ANNTFYGLSA431GVFTKDIDKA441ITISSALQAG
451-500451TVWVNCYGVV461SAQCPFGGFK471MSGNGRELGE481YGFHEYTEVK491TVTVKISQKN
501-501501S
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
126 Prediction (High) - -
133 Prediction (High) - -
163 Prediction (Low) - -
186 Prediction (Medium) - -
276 Prediction (Low) - -
370 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
90 Y → C 0.001764 SNP Missense Mutation LUAD
90 Y → C 0.001887 SNP Missense Mutation UCEC
100 R → C 0.001887 SNP Missense Mutation UCEC
131 R → C 0.001764 SNP Missense Mutation LUAD
131 R → C 0.002506 SNP Missense Mutation COAD
151 F → C 0.001887 SNP Missense Mutation UCEC
395 R → C 0.002288 SNP Missense Mutation STAD
395 R → C 0.002506 SNP Missense Mutation COAD
456 C → S 0.001969 SNP Missense Mutation HNSC
464 C → C 0.002506 SNP Silent COAD
464 C → C 0.001887 SNP Silent UCEC