Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P00441 | SOD1 | Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) … | Homo sapiens (Human) | 154 aa |
Protein Details: P00441 (SOD1)
Protein Information
| Accession | P00441 |
|---|---|
| Protein Names | Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (EC 1.8.-.-) (Hydrogen sulfide oxidase) (Superoxide dismutase 1) (hSod1) |
| Gene Symbol | SOD1 |
| Organism | Homo sapiens (Human) |
| Length | 154 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 |
| Database Sources | PTMDCysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATKAVCVLK11GDGPVQGIIN21FEQKESNGPV31KVWGSIKGLT41EGLHGFHVHE
51-10051FGDNTAGCTS61AGPHFNPLSR71KHGGPKDEER81HVGDLGNVTA91DKDGVADVSI
101-150101EDSVISLSGD111HCIIGRTLVV121HEKADDLGKG131GNEESTKTGN141AGSRLACGVI
151-154151GIAQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | DBPTM SWISSPALM | Superoxide dismutase-like, copper/zinc binding domain superfamily | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.05
|
| 58 | - | - | - |
Deep-Palm: 0.27
|
|
| 112 | DBPTM SWISSPALM | Copper/zinc superoxide dismutase (SODC) | - |
Unknown
(32651440)
|
GPS-Palm: 0.78
Deep-Palm: 0.94
|
| 147 | SWISSPALM DBPTM CYSMODDB | Copper/zinc superoxide dismutase (SODC) |
SW480 cell line
(26865113)
| - |
GPS-Palm: 0.95
Deep-Palm: 0.11
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
EC cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 42 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |