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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P01019 AGT; SERPINA8 Angiotensinogen (Serpin A8) [Cleaved into: … Homo sapiens (Human) 476 aa

Protein Details: P01019 (AGT)

Protein Information
Accession P01019
Protein Names Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4]
Gene Symbol AGT; SERPINA8
Organism Homo sapiens (Human)
Length 476 aa
Isoforms No isoforms
Related PMIDs 32944167 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
PC3 cells
Specificity: 0.500
1/4 (25.0%)
1
Liver membrane
Specificity: 0.500
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAPAGVSLRA11TILCLLAWAG21LAAGDRVYIH31PFHLVIHNES41TCEQLAKANA
51-10051GKPKDPTFIP61APIQAKTSPV71DEKALQDQLV81LVAAKLDTED91KLRAAMVGML
101-150101ANFLGFRIYG111MHSELWGVVH121GATVLSPTAV131FGTLASLYLG141ALDHTADRLQ
151-200151AILGVPWKDK161NCTSRLDAHK171VLSALQAVQG181LLVAQGRADS191QAQLLLSTVV
201-250201GVFTAPGLHL211KQPFVQGLAL221YTPVVLPRSL231DFTELDVAAE241KIDRFMQAVT
251-300251GWKTGCSLMG261ASVDSTLAFN271TYVHFQGKMK281GFSLLAEPQE291FWVDNSTSVS
301-350301VPMLSGMGTF311QHWSDIQDNF321SVTQVPFTES331ACLLLIQPHY341ASDLDKVEGL
351-400351TFQQNSLNWM361KKLSPRTIHL371TMPQLVLQGS381YDLQDLLAQA391ELPAILHTEL
401-450401NLQKLSNDRI411RVGEVLNSIF421FELEADEREP431TESTQQLNKP441EVLEVTLNRP
451-476451FLFAVYDQSA461TALHFLGRVA471NPLSTA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
42 Prediction (Low) - -
162 Prediction (Medium) - -
256 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
116 R → C 0.002141 SNP Missense Mutation SKCM
265 C → C 0.002288 SNP Silent STAD
341 C → F 0.002033 SNP Missense Mutation LUSC
351 S → C 0.001014 SNP Missense Mutation BRCA
411 L → Cfs*4 0.001969 DEL Frame Shift Del LGG