Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P01019 | AGT | Angiotensinogen (Serpin A8) [Cleaved into: … | Homo sapiens (Human) | 476 aa |
Protein Details: P01019 (AGT)
Protein Information
| Accession | P01019 |
|---|---|
| Protein Names | Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4] |
| Gene Symbol | AGT |
| Organism | Homo sapiens (Human) |
| Length | 476 aa |
| Isoforms | No isoforms |
| Related PMIDs | 33636221 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAPAGVSLRA11TILCLLAWAG21LAAGDRVYIH31PFHLVIHNES41TCEQLAKANA
51-10051GKPKDPTFIP61APIQAKTSPV71DEKALQDQLV81LVAAKLDTED91KLRAAMVGML
101-150101ANFLGFRIYG111MHSELWGVVH121GATVLSPTAV131FGTLASLYLG141ALDHTADRLQ
151-200151AILGVPWKDK161NCTSRLDAHK171VLSALQAVQG181LLVAQGRADS191QAQLLLSTVV
201-250201GVFTAPGLHL211KQPFVQGLAL221YTPVVLPRSL231DFTELDVAAE241KIDRFMQAVT
251-300251GWKTGCSLMG261ASVDSTLAFN271TYVHFQGKMK281GFSLLAEPQE291FWVDNSTSVS
301-350301VPMLSGMGTF311QHWSDIQDNF321SVTQVPFTES331ACLLLIQPHY341ASDLDKVEGL
351-400351TFQQNSLNWM361KKLSPRTIHL371TMPQLVLQGS381YDLQDLLAQA391ELPAILHTEL
401-450401NLQKLSNDRI411RVGEVLNSIF421FELEADEREP431TESTQQLNKP441EVLEVTLNRP
451-476451FLFAVYDQSA461TALHFLGRVA471NPLSTA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 14 | - | - | - |
Deep-Palm: 0.97
|
|
| 42 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.27
|
|
| 162 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.95
|
|
| 256 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.59
|
|
| 332 | - | - | - |
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 116 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 265 | C → C | 0.002288 | SNP | Silent | STAD |
| 341 | C → F | 0.002033 | SNP | Missense Mutation | LUSC |
| 351 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 411 | L → Cfs*4 | 0.001969 | DEL | Frame Shift Del | LGG |