Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P01375 TNF; TNFA; TNFSF2 Tumor necrosis factor (Cachectin) (TNF-alpha) … Homo sapiens (Human) 233 aa

Protein Details: P01375 (TNF)

Protein Information
Accession P01375
Protein Names Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene Symbol TNF; TNFA; TNFSF2
Organism Homo sapiens (Human)
Length 233 aa
Isoforms No isoforms
Related PMIDs No related PMIDs
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSTESMIRDV11ELAEEALPKK21TGGPQGSRRC31LFLSLFSFLI41VAGATTLFCL
51-10051LHFGVIGPQR61EEFPRDLSLI71SPLAQAVRSS81SRTPSDKPVA91HVVANPQAEG
101-150101QLQWLNRRAN111ALLANGVELR121DNQLVVPSEG131LYLIYSQVLF141KGQGCPSTHV
151-200151LLTHTISRIA161VSYQTKVNLL171SAIKSPCQRE181TPEGAEAKPW191YEPIYLGGVF
201-233201QLEKGDRLSA211EINRPDYLDF221AESGQVYFGI231IAL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
30 DBPTM SWISSPALM Prediction (Medium) - -
49 DBPTM SWISSPALM Prediction (Low) - -
177 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
30 C → C 0.027027 SNP Silent DLBC
145 C → C 0.001887 SNP Silent UCEC