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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P01730 CD4 T-cell surface glycoprotein CD4 (T-cell … Homo sapiens (Human) 458 aa

Protein Details: P01730 (CD4)

Protein Information
Accession P01730
Protein Names T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4)
Gene Symbol CD4
Organism Homo sapiens (Human)
Length 458 aa
Isoforms No isoforms
Related PMIDs 19137006 26111759
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
6
Jurkat T cells
Specificity: 0.600
6/25 (24.0%)
4
T cells
Specificity: 0.400
4/4 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNRGVPFRHL11LLVLQLALLP21AATQGKKVVL31GKKGDTVELT41CTASQKKSIQ
51-10051FHWKNSNQIK61ILGNQGSFLT71KGPSKLNDRA81DSRRSLWDQG91NFPLIIKNLK
101-150101IEDSDTYICE111VEDQKEEVQL121LVFGLTANSD131THLLQGQSLT141LTLESPPGSS
151-200151PSVQCRSPRG161KNIQGGKTLS171VSQLELQDSG181TWTCTVLQNQ191KKVEFKIDIV
201-250201VLAFQKASSI211VYKKEGEQVE221FSFPLAFTVE231KLTGSGELWW241QAERASSSKS
251-300251WITFDLKNKE261VSVKRVTQDP271KLQMGKKLPL281HLTLPQALPQ291YAGSGNLTLA
301-350301LEAKTGKLHQ311EVNLVVMRAT321QLQKNLTCEV331WGPTSPKLML341SLKLENKEAK
351-400351VSKREKAVWV361LNPEAGMWQC371LLSDSGQVLL381ESNIKVLPTW391STPVQPMALI
401-450401VLGGVAGLLL411FIGLGIFFCV421RCRHRRRQAE431RMSQIKRLLS441EKKTCQCPHR
451-458451FQKTCSPI
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
41 Prediction (Medium) - -
155 Prediction (Low) - -
184 Prediction (Low) - -
328 Prediction (Low) - -
419 DBPTM SWISSPALM Prediction (High) T cell CD4 receptor C terminal region -
422 DBPTM SWISSPALM Prediction (High) T cell CD4 receptor C terminal region -
445 Prediction (High) - -
455 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
72 G → C 0.001887 SNP Missense Mutation UCEC
427 R → C 0.001887 SNP Missense Mutation UCEC