Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P01732 | CD8A | T-cell surface glycoprotein CD8 alpha … | Homo sapiens (Human) | 235 aa |
Protein Details: P01732 (CD8A)
Protein Information
| Accession | P01732 |
|---|---|
| Protein Names | T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a) |
| Gene Symbol | CD8A |
| Organism | Homo sapiens (Human) |
| Length | 235 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MALPVTALLL11PLALLLHAAR21PSQFRVSPLD31RTWNLGETVE41LKCQVLLSNP
51-10051TSGCSWLFQP61RGAAASPTFL71LYLSQNKPKA81AEGLDTQRFS91GKRLGDTFVL
101-150101TLSDFRRENE111GYYFCSALSN121SIMYFSHFVP131VFLPAKPTTT141PAPRPPTPAP
151-200151TIASQPLSLR161PEACRPAAGG171AVHTRGLDFA181CDIYIWAPLA191GTCGVLLLSL
201-235201VITLYCNHRN211RRRVCKCPRP221VVKSGDKPSL231SARYV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 43 | Immunoglobulin-like fold Immunoglobulin-like domain superfamily | - | - |
Deep-Palm: 0.59
|
|
| 54 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.91
|
|
| 115 | - | - | - |
Deep-Palm: 0.14
|
|
| 164 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.95
|
|
| 181 | - | - | - |
Deep-Palm: 0.84
|
|
| 193 | - | - | - |
Deep-Palm: 0.74
|
|
| 206 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.97
|
| 215 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.77
|
|
| 217 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.79
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 106 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 111 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 184 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 213 | R → C | 0.007299 | SNP | Missense Mutation | READ |