Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P01903 | HLA-DRA | HLA class II histocompatibility antigen, … | Homo sapiens (Human) | 254 aa |
Protein Details: P01903 (HLA-DRA)
Protein Information
| Accession | P01903 |
|---|---|
| Protein Names | HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA) |
| Gene Symbol | HLA-DRA |
| Organism | Homo sapiens (Human) |
| Length | 254 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAISGVPVLG11FFIIAVLMSA21QESWAIKEEH31VIIQAEFYLN41PDQSGEFMFD
51-10051FDGDEIFHVD61MAKKETVWRL71EEFGRFASFE81AQGALANIAV91DKANLEIMTK
101-150101RSNYTPITNV111PPEVTVLTNS121PVELREPNVL131ICFIDKFTPP141VVNVTWLRNG
151-200151KPVTTGVSET161VFLPREDHLF171RKFHYLPFLP181STEDVYDCRV191EHWGLDEPLL
201-250201KHWEFDAPSP211LPETTENVVC221ALGLTVGLVG231IIIGTIFIIK241GLRKSNAAER
251-254251RGPL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 132 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.57
|
|
| 188 | - | - | - |
Deep-Palm: 0.66
|
|
| 220 | - | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
CEM 174 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 19 | S → C | 0.017544 | SNP | Missense Mutation | UCS |
| 101 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 171 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 175 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 243 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 250 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 250 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 250 | R → C | 0.002033 | SNP | Missense Mutation | THCA |