Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P02730-2 | SLC4A1 | Band 3 anion transport protein … | Homo sapiens (Human) | 846 aa |
Protein Details: P02730-2 (SLC4A1)
Protein Information
| Accession | P02730-2 |
|---|---|
| Protein Names | Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233) |
| Gene Symbol | SLC4A1 |
| Organism | Homo sapiens (Human) |
| Length | 846 aa |
| Isoforms | |
| Related PMIDs | 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDEKNQELRW11MEAARWVQLE21ENLGENGAWG31RPHLSHLTFW41SLLELRRVFT
51-10051KGTVLLDLQE61TSLAGVANQL71LDRFIFEDQI81RPQDREELLR91ALLLKHSHAG
101-150101ELEALGGVKP111AVLTRSGDPS121QPLLPQHSSL131ETQLFCEQGD141GGTEGHSPSG
151-200151ILEKIPPDSE161ATLVLVGRAD171FLEQPVLGFV181RLQEAAELEA191VELPVPIRFL
201-250201FVLLGPEAPH211IDYTQLGRAA221ATLMSERVFR231IDAYMAQSRG241ELLHSLEGFL
251-300251DCSLVLPPTD261APSEQALLSL271VPVQRELLRR281RYQSSPAKPD291SSFYKGLDLN
301-350301GGPDDPLQQT311GQLFGGLVRD321IRRRYPYYLS331DITDAFSPQV341LAAVIFIYFA
351-400351ALSPAITFGG361LLGEKTRNQM371GVSELLISTA381VQGILFALLG391AQPLLVVGFS
401-450401GPLLVFEEAF411FSFCETNGLE421YIVGRVWIGF431WLILLVVLVV441AFEGSFLVRF
451-500451ISRYTQEIFS461FLISLIFIYE471TFSKLIKIFQ481DHPLQKTYNY491NVLMVPKPQG
501-550501PLPNTALLSL511VLMAGTFFFA521MMLRKFKNSS531YFPGKLRRVI541GDFGVPISIL
551-600551IMVLVDFFIQ561DTYTQKLSVP571DGFKVSNSSA581RGWVIHPLGL591RSEFPIWMMF
601-650601ASALPALLVF611ILIFLESQIT621TLIVSKPERK631MVKGSGFHLD641LLLVVGMGGV
651-700651AALFGMPWLS661ATTVRSVTHA671NALTVMGKAS681TPGAAAQIQE691VKEQRISGLL
701-750701VAVLVGLSIL711MEPILSRIPL721AVLFGIFLYM731GVTSLSGIQL741FDRILLLFKP
751-800751PKYHPDVPYV761KRVKTWRMHL771FTGIQIICLA781VLWVVKSTPA791SLALPFVLIL
801-846801TVPLRRVLLP811LIFRNVELQC821LDADDAKATF831DEEEGRDEYD841EVAMPV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 201 | - | - | - |
Deep-Palm: 0.89
|
|
| 317 | - | - | - |
Deep-Palm: 0.98
|
|
| 479 | - | - | - |
Deep-Palm: 0.68
|
|
| 843 | - | - | - |
Deep-Palm: 0.69
|
|
| 885 | - | - | - |
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 173 | V → Cfs*30 | 0.002288 | INS | Frame Shift Ins | STAD |
| 180 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 346 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 346 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 346 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 384 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 389 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 476 | F → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 483 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 490 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 514 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 713 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |