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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P02749 APOH; B2G1 Beta-2-glycoprotein 1 (APC inhibitor) (Activated … Homo sapiens (Human) 345 aa

Protein Details: P02749 (APOH)

Protein Information
Accession P02749
Protein Names Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)
Gene Symbol APOH; B2G1
Organism Homo sapiens (Human)
Length 345 aa
Isoforms No isoforms
Related PMIDs 31251020 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.833
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
5
LNCaP cells
Specificity: 0.833
5/46 (10.9%)
1
Liver membrane
Specificity: 0.167
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MISPVLILFS11SFLCHVAIAG21RTCPKPDDLP31FSTVVPLKTF41YEPGEEITYS
51-10051CKPGYVSRGG61MRKFICPLTG71LWPINTLKCT81PRVCPFAGIL91ENGAVRYTTF
101-150101EYPNTISFSC111NTGFYLNGAD121SAKCTEEGKW131SPELPVCAPI141ICPPPSIPTF
151-200151ATLRVYKPSA161GNNSLYRDTA171VFECLPQHAM181FGNDTITCTT191HGNWTKLPEC
201-250201REVKCPFPSR211PDNGFVNYPA221KPTLYYKDKA231TFGCHDGYSL241DGPEEIECTK
251-300251LGNWSAMPSC261KASCKVPVKK271ATVVYQGERV281KIQEKFKNGM291LHGDKVSFFC
301-345301KNKEKKCSYT311EDAQCIDGTI321EVPKCFKEHS331SLAFWKTDAS341DVKPC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
66 Prediction (High) - -
79 Prediction (Low) - -
84 Prediction (High) - -
260 Prediction (Medium) - -
264 Prediction (Low) - -
300 Prediction (Low) - -
345 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
55 Y → C 0.001887 SNP Missense Mutation UCEC
96 R → C 0.001887 SNP Missense Mutation UCEC
110 C → C 0.002033 SNP Silent LUSC
154 R → C 0.001969 SNP Missense Mutation HNSC
154 R → C 0.001887 SNP Missense Mutation UCEC
205 C → Y 0.002545 SNP Missense Mutation GBM
242 G → C 0.002294 SNP Missense Mutation OV
307 C → Y 0.003460 SNP Missense Mutation CESC
315 C → Y 0.001887 SNP Missense Mutation UCEC
315* C → ? 0.002033 SNP Nonsense Mutation LUSC