Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P02786 | TFRC | Transferrin receptor protein 1 (TR) … | Homo sapiens (Human) | 760 aa |
Protein Details: P02786 (TFRC)
Protein Information
| Accession | P02786 |
|---|---|
| Protein Names | Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] |
| Gene Symbol | TFRC |
| Organism | Homo sapiens (Human) |
| Length | 760 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 22496122 24357059 25914232 26111759 29575903 29733200 31251020 31382980 32651440 32944167 33636221 36430497 37611173 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.523
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
46
LNCaP cells
Specificity: 0.523
46/46 (100.0%)
10
HAP1 cells
Specificity: 0.114
10/10 (100.0%)
7
Jurkat T cells
Specificity: 0.080
7/25 (28.0%)
6
293T cells
Specificity: 0.068
6/10 (60.0%)
4
PC3 cells
Specificity: 0.045
4/4 (100.0%)
4
T cells
Specificity: 0.045
4/4 (100.0%)
3
CEMx174 cells
Specificity: 0.034
3/3 (100.0%)
2
DU145 cells
Specificity: 0.023
2/2 (100.0%)
2
Endothelial cells
Specificity: 0.023
2/2 (100.0%)
1
U937 cells
Specificity: 0.011
1/1 (100.0%)
1
HeLa cells
Specificity: 0.011
1/1 (100.0%)
1
Cerebral cortex
Specificity: 0.011
1/4 (25.0%)
1
Liver membrane
Specificity: 0.011
1/1 (100.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MMDQARSAFS11NLFGGEPLSY21TRFSLARQVD31GDNSHVEMKL41AVDEEENADN
51-10051NTKANVTKPK61RCSGSICYGT71IAVIVFFLIG81FMIGYLGYCK91GVEPKTECER
101-150101LAGTESPVRE111EPGEDFPAAR121RLYWDDLKRK131LSEKLDSTDF141TGTIKLLNEN
151-200151SYVPREAGSQ161KDENLALYVE171NQFREFKLSK181VWRDQHFVKI191QVKDSAQNSV
201-250201IIVDKNGRLV211YLVENPGGYV221AYSKAATVTG231KLVHANFGTK241KDFEDLYTPV
251-300251NGSIVIVRAG261KITFAEKVAN271AESLNAIGVL281IYMDQTKFPI291VNAELSFFGH
301-350301AHLGTGDPYT311PGFPSFNHTQ321FPPSRSSGLP331NIPVQTISRA341AAEKLFGNME
351-400351GDCPSDWKTD361STCRMVTSES371KNVKLTVSNV381LKEIKILNIF391GVIKGFVEPD
401-450401HYVVVGAQRD411AWGPGAAKSG421VGTALLLKLA431QMFSDMVLKD441GFQPSRSIIF
451-500451ASWSAGDFGS461VGATEWLEGY471LSSLHLKAFT481YINLDKAVLG491TSNFKVSASP
501-550501LLYTLIEKTM511QNVKHPVTGQ521FLYQDSNWAS531KVEKLTLDNA541AFPFLAYSGI
551-600551PAVSFCFCED561TDYPYLGTTM571DTYKELIERI581PELNKVARAA591AEVAGQFVIK
601-650601LTHDVELNLD611YERYNSQLLS621FVRDLNQYRA631DIKEMGLSLQ641WLYSARGDFF
651-700651RATSRLTTDF661GNAEKTDRFV671MKKLNDRVMR681VEYHFLSPYV691SPKESPFRHV
701-750701FWGSGSHTLP711ALLENLKLRK721QNNGAFNETL731FRNQLALATW741TIQGAANALS
751-760751GDVWDIDNEF
Palmitoylation Sites Details
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 152 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 174 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 174 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 174 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 321 | F → delinsLEYVALILIC | 0.002294 | INS | In Frame Ins | OV |
| 338 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 646 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 719 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 719 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 719 | R → C | 0.003460 | SNP | Missense Mutation | CESC |