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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P04003 C4BPA; C4BP C4b-binding protein alpha chain (C4bp) … Homo sapiens (Human) 597 aa

Protein Details: P04003 (C4BPA)

Protein Information
Accession P04003
Protein Names C4b-binding protein alpha chain (C4bp) (Proline-rich protein) (PRP)
Gene Symbol C4BPA; C4BP
Organism Homo sapiens (Human)
Length 597 aa
Isoforms No isoforms
Related PMIDs 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Liver membrane
Specificity: 1.000
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MHPPKTPSGA11LHRKRKMAAW21PFSRLWKVSD31PILFQMTLIA41ALLPAVLGNC
51-10051GPPPTLSFAA61PMDITLTETR71FKTGTTLKYT81CLPGYVRSHS91TQTLTCNSDG
101-150101EWVYNTFCIY111KRCRHPGELR121NGQVEIKTDL131SFGSQIEFSC141SEGFFLIGST
151-200151TSRCEVQDRG161VGWSHPLPQC171EIVKCKPPPD181IRNGRHSGEE191NFYAYGFSVT
201-250201YSCDPRFSLL211GHASISCTVE221NETIGVWRPS231PPTCEKITCR241KPDVSHGEMV
251-300251SGFGPIYNYK261DTIVFKCQKG271FVLRGSSVIH281CDADSKWNPS291PPACEPNSCI
301-350301NLPDIPHASW311ETYPRPTKED321VYVVGTVLRY331RCHPGYKPTT341DEPTTVICQK
351-400351NLRWTPYQGC361EALCCPEPKL371NNGEITQHRK381SRPANHCVYF391YGDEISFSCH
401-450401ETSRFSAICQ411GDGTWSPRTP421SCGDICNFPP431KIAHGHYKQS441SSYSFFKEEI
451-500451IYECDKGYIL461VGQAKLSCSY471SHWSAPAPQC481KALCRKPELV491NGRLSVDKDQ
501-550501YVEPENVTIQ511CDSGYGVVGP521QSITCSGNRT531WYPEVPKCEW541ETPEGCEQVL
551-597551TGKRLMQCLP561NPEDVKMALE571VYKLSLEIEQ581LELQRDSARQ591STLDKEL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
81 Prediction (Medium) - -
108 Prediction (Low) - -
113 Prediction (Low) - -
154 Prediction (Low) - -
267 Prediction (Low) - -
281 Prediction (Low) - -
348 Prediction (Low) - -
360 Prediction (Medium) - -
409 Prediction (Low) - -
468 Prediction (Low) - -
484 Prediction (Medium) - -
546 Prediction (Medium) - -
558 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
70 R → C 0.001969 SNP Missense Mutation HNSC
154 C → F 0.001887 SNP Missense Mutation UCEC
198 S → C 0.002427 SNP Missense Mutation BLCA
234 C → Lfs*3 0.001887 INS Nonsense Mutation UCEC
267 C → F 0.001764 SNP Missense Mutation LUAD
267 C → F 0.002033 SNP Missense Mutation LUSC
361 E → _A362insCL 0.001969 INS In Frame Ins HNSC
364 C → G 0.001887 SNP Missense Mutation UCEC
391 Y → C 0.003460 SNP Missense Mutation CESC
409 C → C 0.001887 SNP Silent UCEC
591 S → C 0.002141 SNP Missense Mutation SKCM