Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P04216 | THY1 | Thy-1 membrane glycoprotein (CDw90) (Thy-1 … | Homo sapiens (Human) | 161 aa |
Protein Details: P04216 (THY1)
Protein Information
| Accession | P04216 |
|---|---|
| Protein Names | Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90) |
| Gene Symbol | THY1 |
| Organism | Homo sapiens (Human) |
| Length | 161 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNLAISIALL11LTVLQVSRGQ21KVTSLTACLV31DQSLRLDCRH41ENTSSSPIQY
51-10051EFSLTRETKK61HVLFGTVGVP71EHTYRSRTNF81TSKYNMKVLY91LSAFTSKDEG
101-150101TYTCALHHSG111HSPPISSQNV121TVLRDKLVKC131EGISLLAQNT141SWLLLLLLSL
151-161151SLLQATDFMS161L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 28 | SWISSPALM DBPTM CYSMODDB | Thy-1 membrane glycoprotein |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.93
Deep-Palm: 0.85
|
| 38 | Thy-1 membrane glycoprotein | - | - |
Deep-Palm: 0.69
|
|
| 104 | - | - | - |
Deep-Palm: 0.31
|
|
| 130 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
3
CEM 174 cell
Specificity: 0.273
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.364
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 56 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 75 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 104 | C → C | 0.002747 | SNP | Silent | LIHC |