Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P04217 | A1BG | Alpha-1B-glycoprotein (Alpha-1-B glycoprotein) | Homo sapiens (Human) | 495 aa |
Protein Details: P04217 (A1BG)
Protein Information
| Accession | P04217 |
|---|---|
| Protein Names | Alpha-1B-glycoprotein (Alpha-1-B glycoprotein) |
| Gene Symbol | A1BG |
| Organism | Homo sapiens (Human) |
| Length | 495 aa |
| Isoforms | No isoforms |
| Related PMIDs | 33636221 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSMLVVFLLL11WGVTWGPVTE21AAIFYETQPS31LWAESESLLK41PLANVTLTCQ
51-10051AHLETPDFQL61FKNGVAQEPV71HLDSPAIKHQ81FLLTGDTQGR91YRCRSGLSTG
101-150101WTQLSKLLEL111TGPKSLPAPW121LSMAPVSWIT131PGLKTTAVCR141GVLRGVTFLL
151-200151RREGDHEFLE161VPEAQEDVEA171TFPVHQPGNY181SCSYRTDGEG191ALSEPSATVT
201-250201IEELAAPPPP211VLMHHGESSQ221VLHPGNKVTL231TCVAPLSGVD241FQLRRGEKEL
251-300251LVPRSSTSPD261RIFFHLNAVA271LGDGGHYTCR281YRLHDNQNGW291SGDSAPVELI
301-350301LSDETLPAPE311FSPEPESGRA321LRLRCLAPLE331GARFALVRED341RGGRRVHRFQ
351-400351SPAGTEALFE361LHNISVADSA371NYSCVYVDLK381PPFGGSAPSE391RLELHVDGPP
401-450401PRPQLRATWS411GAVLAGRDAV421LRCEGPIPDV431TFELLREGET441KAVKTVRTPG
451-495451AAANLELIFV461GPQHAGNYRC471RYRSWVPHTF481ESELSDPVEL491LVAES
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 49 | Immunoglobulin-like fold Immunoglobulin-like domain superfamily | - | - |
Deep-Palm: 0.92
|
|
| 93 | - | - | - |
Deep-Palm: 0.88
|
|
| 139 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.97
|
|
| 182 | - | - | - |
Deep-Palm: 0.71
|
|
| 232 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.89
|
|
| 279 | - | - | - |
Deep-Palm: 0.13
|
|
| 325 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.99
|
|
| 374 | - | - | - |
Deep-Palm: 0.55
|
|
| 423 | - | - | - |
Deep-Palm: 0.97
|
|
| 470 | - | - | - |
Deep-Palm: 0.22
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 90 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 182 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 245 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 261 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 261 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |