Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P04264 KRT1; KRTA Keratin, type II cytoskeletal 1 … Homo sapiens (Human) 644 aa

Protein Details: P04264 (KRT1)

Protein Information
Accession P04264
Protein Names Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene Symbol KRT1; KRTA
Organism Homo sapiens (Human)
Length 644 aa
Isoforms No isoforms
Related PMIDs 25914232 29733200 31382980 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
10
HAP1 cells
Specificity: 0.556
10/10 (100.0%)
4
PC3 cells
Specificity: 0.222
4/4 (100.0%)
3
CEMx174 cells
Specificity: 0.167
3/3 (100.0%)
1
U937 cells
Specificity: 0.056
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSRQFSSRSG11YRSGGGFSSG21SAGIINYQRR31TTSSSTRRSG41GGGGRFSSCG
51-10051GGGGSFGAGG61GFGSRSLVNL71GGSKSISISV81ARGGGRGSGF91GGGYGGGGFG
101-150101GGGFGGGGFG111GGGIGGGGFG121GFGSGGGGFG131GGGFGGGGYG141GGYGPVCPPG
151-200151GIQEVTINQS161LLQPLNVEID171PEIQKVKSRE181REQIKSLNNQ191FASFIDKVRF
201-250201LEQQNQVLQT211KWELLQQVDT221STRTHNLEPY231FESFINNLRR241RVDQLKSDQS
251-300251RLDSELKNMQ261DMVEDYRNKY271EDEINKRTNA281ENEFVTIKKD291VDGAYMTKVD
301-350301LQAKLDNLQQ311EIDFLTALYQ321AELSQMQTQI331SETNVILSMD341NNRSLDLDSI
351-400351IAEVKAQYED361IAQKSKAEAE371SLYQSKYEEL381QITAGRHGDS391VRNSKIEISE
401-450401LNRVIQRLRS411EIDNVKKQIS421NLQQSISDAE431QRGENALKDA441KNKLNDLEDA
451-500451LQQAKEDLAR461LLRDYQELMN471TKLALDLEIA481TYRTLLEGEE491SRMSGECAPN
501-550501VSVSVSTSHT511TISGGGSRGG521GGGGYGSGGS531SYGSGGGSYG541SGGGGGGGRG
551-600551SYGSGGSSYG561SGGGSYGSGG571GGGGHGSYGS581GSSSGGYRGG591SGGGGGGSSG
601-644601GRGSGGGSSG611GSIGGRGSSS621GGVKSSGGSS631SVKFVSTTYS641GVTR
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
49 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
16 G → C 0.002747 SNP Missense Mutation LIHC
20 G → C 0.002033 SNP Missense Mutation LUSC
29 R → C 0.001014 SNP Missense Mutation BRCA
29 R → C 0.005013 SNP Missense Mutation COAD
29 R → C 0.001969 SNP Missense Mutation LGG
89 G → C 0.001887 SNP Missense Mutation UCEC
144 G → C 0.002747 SNP Missense Mutation LIHC
230 Y → C 0.002033 SNP Missense Mutation LUSC
324 S → C 0.003460 SNP Missense Mutation CESC
343 R → C 0.001014 SNP Missense Mutation BRCA
403 R → C 0.003460 SNP Missense Mutation CESC
432 R → C 0.001887 SNP Missense Mutation UCEC
463 R → C 0.002506 SNP Missense Mutation COAD
605 G → C 0.001969 SNP Missense Mutation HNSC