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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P04843 RPN1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein … Homo sapiens (Human) 607 aa

Protein Details: P04843 (RPN1)

Protein Information
Accession P04843
Protein Names Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1)
Gene Symbol RPN1
Organism Homo sapiens (Human)
Length 607 aa
Isoforms No isoforms
Related PMIDs 21076176 29575903 29733200 31251020 32944167 33636221
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.562
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.562
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.156
10/10 (100.0%)
10
293T cells
Specificity: 0.156
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.062
4/25 (16.0%)
3
PC3 cells
Specificity: 0.047
3/4 (75.0%)
1
Liver membrane
Specificity: 0.016
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEAPAAGLFL11LLLLGTWAPA21PGSASSEAPP31LINEDVKRTV41DLSSHLAKVT
51-10051AEVVLAHLGG61GSTSRATSFL71LALEPELEAR81LAHLGVQVKG91EDEEENNLEV
101-150101RETKIKGKSG111RFFTVKLPVA121LDPGAKISVI131VETVYTHVLH141PYPTQITQSE
151-200151KQFVVFEGNH161YFYSPYPTKT171QTMRVKLASR181NVESYTKLGN191PTRSEDLLDY
201-250201GPFRDVPAYS211QDTFKVHYEN221NSPFLTITSM231TRVIEVSHWG241NIAVEENVDL
251-300251KHTGAVLKGP261FSRYDYQRQP271DSGISSIRSF281KTILPAAAQD291VYYRDEIGNV
301-350301STSHLLILDD311SVEMEIRPRF321PLFGGWKTHY331IVGYNLPSYE341YLYNLGDQYA
351-400351LKMRFVDHVF361DEQVIDSLTV371KIILPEGAKN381IEIDSPYEIS391RAPDELHYTY
401-450401LDTFGRPVIV411AYKKNLVEQH421IQDIVVHYTF431NKVLMLQEPL441LVVAAFYILF
451-500451FTVIIYVRLD461FSITKDPAAE471ARMKVACITE481QVLTLVNKRI491GLYRHFDETV
501-550501NRYKQSRDIS511TLNSGKKSLE521TEHKALTSEI531ALLQSRLKTE541GSDLCDRVSE
551-600551MQKLDAQVKE561LVLKSAVEAE571RLVAGKLKKD581TYIENEKLIS591GKRQELVTKI
601-607601DHILDAL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
477 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) - 29575903
545 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
101 R → C 0.002506 SNP Missense Mutation COAD
263 R → C 0.002033 SNP Missense Mutation LUSC
406 R → C 0.001969 SNP Missense Mutation LGG