Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P05141 SLC25A5 ADP/ATP translocase 2 (ADP,ATP carrier … Homo sapiens (Human) 298 aa

Protein Details: P05141 (SLC25A5)

Protein Information
AccessionP05141
Protein NamesADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene SymbolSLC25A5
OrganismHomo sapiens (Human)
Length298 aa
IsoformsNo isoforms
Related PMIDs 21076176 29733200 31251020 32944167 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTDAAVSFAK11DFLAGGVAAA21ISKTAVAPIE31RVKLLLQVQH41ASKQITADKQ
51-10051YKGIIDCVVR61IPKEQGVLSF71WRGNLANVIR81YFPTQALNFA91FKDKYKQIFL
101-150101GGVDKRTQFW111LYFAGNLASG121GAAGATSLCF131VYPLDFARTR141LAADVGKAGA
151-200151EREFRGLGDC161LVKIYKSDGI171KGLYQGFNVS181VQGIIIYRAA191YFGIYDTAKG
201-250201MLPDPKNTHI211VISWMIAQTV221TAVAGLTSYP231FDTVRRRMMM241QSGRKGTDIM
251-298251YTGTLDCWRK261IARDEGGKAF271FKGAWSNVLR281GMGGAFVLVL291YDEIKKYT
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
57 - - -
GPS-Palm: 0.87
Deep-Palm: 0.98
129 - - -
GPS-Palm: 0.78
Deep-Palm: 0.98
160 SWISSPALM DBPTM CYSMODDB Mitochondrial carrier protein -
cerebral cortex (36430497)
GPS-Palm: 0.88
Deep-Palm: 0.98
257 - -
LNCaP (31251020)
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.83
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.200
3
LNCaP
Specificity: 0.150
3/3 (100.0%)
3
PC3
Specificity: 0.150
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.150
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.100
2/2 (100.0%)
2
293T cell
Specificity: 0.100
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.050
1/1 (100.0%)
1
heart
Specificity: 0.050
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
Cerebral Cortex (Mass)
Specificity: 0.150
3/4 (75.0%)
2
LNCaP cells (Mass)
Specificity: 0.100
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine