Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P05213 Tuba1b Tubulin alpha-1B chain (EC 3.6.5.-) … Mus musculus (Mouse) 451 aa

Protein Details: P05213 (Tuba1b)

Protein Information
AccessionP05213
Protein NamesTubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin 2) (Alpha-tubulin isotype M-alpha-2) (Tubulin alpha-2 chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene SymbolTuba1b
OrganismMus musculus (Mouse)
Length451 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRECISIHVG11QAGVQIGNAC21WELYCLEHGI31QPDGQMPSDK41TIGGGDDSFN
51-10051TFFSETGAGK61HVPRAVFVDL71EPTVIDEVRT81GTYRQLFHPE91QLITGKEDAA
101-150101NNYARGHYTI111GKEIIDLVLD121RIRKLADQCT131GLQGFLVFHS141FGGGTGSGFT
151-200151SLLMERLSVD161YGKKSKLEFS171IYPAPQVSTA181VVEPYNSILT191THTTLEHSDC
201-250201AFMVDNEAIY211DICRRNLDIE221RPTYTNLNRL231ISQIVSSITA241SLRFDGALNV
251-300251DLTEFQTNLV261PYPRIHFPLA271TYAPVISAEK281AYHEQLSVAE291ITNACFEPAN
301-350301QMVKCDPRHG311KYMACCLLYR321GDVVPKDVNA331AIATIKTKRS341IQFVDWCPTG
351-400351FKVGINYQPP361TVVPGGDLAK371VQRAVCMLSN381TTAIAEAWAR391LDHKFDLMYA
401-450401KRAFVHWYVG411EGMEEGEFSE421AREDMAALEK431DYEEVGVDSV441EGEGEEEGEE
451-451451Y
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 Tubulin/FtsZ, GTPase domain superfamily -
Brain (35358180)
GPS-Palm: 0.94
Deep-Palm: 0.03
20 Tubulin/FtsZ, GTPase domain OS01G0282866 PROTEIN Tubulin/FtsZ, GTPase domain superfamily -
Brain (35358180)
Deep-Palm: 0.40
25 Alpha tubulin Tubulin/FtsZ, GTPase domain OS01G0282866 PROTEIN Tubulin/FtsZ, GTPase domain superfamily -
Brain (35358180)
Deep-Palm: 0.19
129 - -
Brain (35358180)
Deep-Palm: 0.74
200 - - -
Deep-Palm: 0.07
213 - - -
GPS-Palm: 0.79
Deep-Palm: 0.16
295 Tubulin C-terminal domain
Brain (34200797)
Liver (34884899)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.24
305 Tubulin C-terminal domain
Brain (34200797)
-
Deep-Palm: 0.17
315 Tubulin C-terminal domain
Brain (34200797)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.85
Deep-Palm: 0.59
316 - -
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.93
Deep-Palm: 0.78
347 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.84
Deep-Palm: 0.29
376 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
Liver
Specificity: 0.044
2/2 (100.0%)
2
Brain
Specificity: 0.044
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
41
Brain tissue (Mass)
Specificity: 0.911
41/56 (73.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine