Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P06151 | Ldha | L-lactate dehydrogenase A chain (LDH-A) … | Mus musculus (Mouse) | 332 aa |
Protein Details: P06151 (Ldha)
Protein Information
| Accession | P06151 |
|---|---|
| Protein Names | L-lactate dehydrogenase A chain (LDH-A) (EC 1.1.1.27) (LDH muscle subunit) (LDH-M) |
| Gene Symbol | Ldha |
| Organism | Mus musculus (Mouse) |
| Length | 332 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATLKDQLIV11NLLKEEQAPQ21NKITVVGVGA31VGMACAISIL41MKDLADELAL
51-10051VDVMEDKLKG61EMMDLQHGSL71FLKTPKIVSS81KDYCVTANSK91LVIITAGARQ
101-150101QEGESRLNLV111QRNVNIFKFI121IPNIVKYSPH131CKLLIVSNPV141DILTYVAWKI
151-200151SGFPKNRVIG161SGCNLDSARF171RYLMGERLGV181HALSCHGWVL191GEHGDSSVPV
201-250201WSGVNVAGVS211LKSLNPELGT221DADKEQWKEV231HKQVVDSAYE241VIKLKGYTSW
251-300251AIGLSVADLA261ESIMKNLRRV271HPISTMIKGL281YGINEDVFLS291VPCILGQNGI
301-332301SDVVKVTLTP311EEEARLKKSA321DTLWGIQKEL331QF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 35 | L-lactate/malate dehydrogenase L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) NAD(P)-binding domain superfamily Lactate/malate dehydrogenase, N-terminal | - |
Brain
(35358180)
|
GPS-Palm: 0.84
Deep-Palm: 0.96
|
|
| 84 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase, NAD binding domain |
brain
(39008777)
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.75
Deep-Palm: 0.97
|
| 131 | - | - | - |
Deep-Palm: 0.90
|
|
| 163 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase NAD binding domain |
Liver
(28526873)
Brain
(34200797)
|
Liver
(37925639)
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.95
Deep-Palm: 0.97
|
| 185 | lactate/malate dehydrogenase alpha/beta C-terminal domain |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 293 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase alpha/beta C-terminal domain |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Liver
Specificity: 0.096
5/5 (100.0%)
4
Brain
Specificity: 0.077
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.953
41
Brain tissue (Mass)
Specificity: 0.788
41/56 (73.2%)
2
Liver tissue (Mass)
Specificity: 0.038
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.