Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P06732 | CKM; CKMM | Creatine kinase M-type (EC 2.7.3.2) … | Homo sapiens (Human) | 381 aa |
Protein Details: P06732 (CKM)
Protein Information
| Accession | P06732 |
|---|---|
| Protein Names | Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) |
| Gene Symbol | CKM; CKMM |
| Organism | Homo sapiens (Human) |
| Length | 381 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.960
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.960
24/46 (52.2%)
1
Liver membrane
Specificity: 0.040
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPFGNTHNKF11KLNYKPEEEY21PDLSKHNNHM31AKVLTLELYK41KLRDKETPSG
51-10051FTVDDVIQTG61VDNPGHPFIM71TVGCVAGDEE81SYEVFKELFD91PIISDRHGGY
101-150101KPTDKHKTDL111NHENLKGGDD121LDPNYVLSSR131VRTGRSIKGY141TLPPHCSRGE
151-200151RRAVEKLSVE161ALNSLTGEFK171GKYYPLKSMT181EKEQQQLIDD191HFLFDKPVSP
201-250201LLLASGMARD211WPDARGIWHN221DNKSFLVWVN231EEDHLRVISM241EKGGNMKEVF
251-300251RRFCVGLQKI261EEIFKKAGHP271FMWNQHLGYV281LTCPSNLGTG291LRGGVHVKLA
301-350301HLSKHPKFEE311ILTRLRLQKR321GTGGVDTAAV331GSVFDVSNAD341RLGSSEVEQV
351-381351QLVVDGVKLM361VEMEKKLEKG371QSIDDMIPAQ381K
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 146 | Prediction (High) | - | - |
| 254 | Prediction (High) | - | - |
| 283 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 130 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 250 | F → C | 0.002288 | SNP | Missense Mutation | STAD |
| 252 | R → C | 0.017544 | SNP | Missense Mutation | UCS |
| 314 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |