Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P06734 | FCER2 | Low affinity immunoglobulin epsilon Fc … | Homo sapiens (Human) | 321 aa |
Protein Details: P06734 (FCER2)
Protein Information
| Accession | P06734 |
|---|---|
| Protein Names | Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form] |
| Gene Symbol | FCER2 |
| Organism | Homo sapiens (Human) |
| Length | 321 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEEGQYSEIE11ELPRRRCCRR21GTQIVLLGLV31TAALWAGLLT41LLLLWHWDTT
51-10051QSLKQLEERA61ARNVSQVSKN71LESHHGDQMA81QKSQSTQISQ91ELEELRAEQQ
101-150101RLKSQDLELS111WNLNGLQADL121SSFKSQELNE131RNEASDLLER141LREEVTKLRM
151-200151ELQVSSGFVC161NTCPEKWINF171QRKCYYFGKG181TKQWVHARYA191CDDMEGQLVS
201-250201IHSPEEQDFL211TKHASHTGSW221IGLRNLDLKG231EFIWVDGSHV241DYSNWAPGEP
251-300251TSRSQGEDCV261MMRGSGRWND271AFCDRKLGAW281VCDRLATCTP291PASEGSAESM
301-321301GPDSRPDPDG311RLPTPSAPLH321S
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.98
|
| 18 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.98
|
| 160 | - | - | - |
Deep-Palm: 0.40
|
|
| 163 | - | - | - |
Deep-Palm: 0.11
|
|
| 174 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.04
|
|
| 191 | - | - | - |
Deep-Palm: 0.17
|
|
| 259 | - | - | - |
Deep-Palm: 0.11
|
|
| 273 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.26
|
|
| 282 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.70
|
|
| 288 | - | - | - |
Deep-Palm: 0.91
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
CEM 174 cell
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 282 | C → C | 0.001887 | SNP | Silent | UCEC |