Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P06797 | Ctsl | Procathepsin L (EC 3.4.22.15) (Cathepsin … | Mus musculus (Mouse) | 334 aa |
Protein Details: P06797 (Ctsl)
Protein Information
| Accession | P06797 |
|---|---|
| Protein Names | Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) (p39 cysteine proteinase) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain] |
| Gene Symbol | Ctsl |
| Organism | Mus musculus (Mouse) |
| Length | 334 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34200797 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNLLLLLAVL11CLGTALATPK21FDQTFSAEWH31QWKSTHRRLY41GTNEEEWRRA
51-10051IWEKNMRMIQ61LHNGEYSNGQ71HGFSMEMNAF81GDMTNEEFRQ91VVNGYRHQKH
101-150101KKGRLFQEPL111MLKIPKSVDW121REKGCVTPVK131NQGQCGSCWA141FSASGCLEGQ
151-200151MFLKTGKLIS161LSEQNLVDCS171HAQGNQGCNG181GLMDFAFQYI191KENGGLDSEE
201-250201SYPYEAKDGS211CKYRAEFAVA221NDTGFVDIPQ231QEKALMKAVA241TVGPISVAMD
251-300251ASHPSLQFYS261SGIYYEPNCS271SKNLDHGVLL281VGYGYEGTDS291NKNKYWLVKN
301-334301SWGSEWGMEG311YIKIAKDRDN321HCGLATAASY331PVVN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 11 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.65
|
|
| 125 | - |
brain
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.66
|
|
| 135 | - | - | - |
Deep-Palm: 0.09
|
|
| 138 | - | - | - |
Deep-Palm: 0.10
|
|
| 146 | - | - | - |
Deep-Palm: 0.27
|
|
| 169 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.58
|
|
| 178 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.08
|
|
| 211 | - | - | - |
Deep-Palm: 0.40
|
|
| 269 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.17
|
|
| 322 | SWISSPALM DBPTM CYSMODDB | Papain family cysteine protease |
brain
(39008777)
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.78
Deep-Palm: 0.07
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Liver
Specificity: 0.211
4/4 (100.0%)
1
Brain
Specificity: 0.053
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
14
Brain tissue (Mass)
Specificity: 0.737
14/56 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.