Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P07195 | LDHB | L-lactate dehydrogenase B chain (LDH-B) … | Homo sapiens (Human) | 334 aa |
Protein Details: P07195 (LDHB)
Protein Information
| Accession | P07195 |
|---|---|
| Protein Names | L-lactate dehydrogenase B chain (LDH-B) (EC 1.1.1.27) (LDH heart subunit) (LDH-H) (Renal carcinoma antigen NY-REN-46) |
| Gene Symbol | LDHB |
| Organism | Homo sapiens (Human) |
| Length | 334 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 22496122 29733200 31251020 31382980 32944167 33636221 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.453
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.453
24/46 (52.2%)
10
HAP1 cells
Specificity: 0.189
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.075
4/25 (16.0%)
4
PC3 cells
Specificity: 0.075
4/4 (100.0%)
4
293T cells
Specificity: 0.075
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.075
4/4 (100.0%)
1
U937 cells
Specificity: 0.019
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.019
1/2 (50.0%)
1
Liver membrane
Specificity: 0.019
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATLKEKLIA11PVAEEEATVP21NNKITVVGVG31QVGMACAISI41LGKSLADELA
51-10051LVDVLEDKLK61GEMMDLQHGS71LFLQTPKIVA81DKDYSVTANS91KIVVVTAGVR
101-150101QQEGESRLNL111VQRNVNVFKF121IIPQIVKYSP131DCIIIVVSNP141VDILTYVTWK
151-200151LSGLPKHRVI161GSGCNLDSAR171FRYLMAEKLG181IHPSSCHGWI191LGEHGDSSVA
201-250201VWSGVNVAGV211SLQELNPEMG221TDNDSENWKE231VHKMVVESAY241EVIKLKGYTN
251-300251WAIGLSVADL261IESMLKNLSR271IHPVSTMVKG281MYGIENEVFL291SLPCILNARG
301-334301LTSVINQKLK311DDEVAQLKKS321ADTLWDIQKD331LKDL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 36 | Prediction (Medium) | - | - |
| 164 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 294 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 100 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 158 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 204 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| ? | ? → ? | 0.002506 | SNP | Nonstop Mutation | COAD |