Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P07306 | ASGR1 | Asialoglycoprotein receptor 1 (ASGP-R 1) … | Homo sapiens (Human) | 291 aa |
Protein Details: P07306 (ASGR1)
Protein Information
| Accession | P07306 |
|---|---|
| Protein Names | Asialoglycoprotein receptor 1 (ASGP-R 1) (ASGPR 1) (C-type lectin domain family 4 member H1) (Hepatic lectin H1) (HL-1) |
| Gene Symbol | ASGR1 |
| Organism | Homo sapiens (Human) |
| Length | 291 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTKEYQDLQH11LDNEESDHHQ21LRKGPPPPQP31LLQRLCSGPR41LLLLSLGLSL
51-10051LLLVVVCVIG61SQNSQLQEEL71RGLRETFSNF81TASTEAQVKG91LSTQGGNVGR
101-150101KMKSLESQLE111KQQKDLSEDH121SSLLLHVKQF131VSDLRSLSCQ141MAALQGNGSE
151-200151RTCCPVNWVE161HERSCYWFSR171SGKAWADADN181YCRLEDAHLV191VVTSWEEQKF
201-250201VQHHIGPVNT211WMGLHDQNGP221WKWVDGTDYE231TGFKNWRPEQ241PDDWYGHGLG
251-291251GGEDCAHFTD261DGRWNDDVCQ271RPYRWVCETE281LDKASQEPPL291L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 36 | DBPTM SWISSPALM | Hepatic lectin, N-terminal domain Hepatic lectin N-terminal domain | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.99
|
| 57 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.98
|
|
| 139 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.87
|
|
| 153 | - | - | - |
Deep-Palm: 0.05
|
|
| 154 | - | - | - |
Deep-Palm: 0.06
|
|
| 165 | - | - | - |
Deep-Palm: 0.07
|
|
| 182 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.41
|
|
| 255 | - | - | - |
Deep-Palm: 0.04
|
|
| 269 | - | - | - |
Deep-Palm: 0.10
|
|
| 277 | - | - | - |
Deep-Palm: 0.44
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 40 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 158 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 200 | F → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 211 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 255* | C → ? | 0.002545 | SNP | Nonsense Mutation | GBM |