Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P07437 TUBB; TUBB5; OK/SW-cl.56 Tubulin beta chain (Tubulin beta-5 … Homo sapiens (Human) 444 aa

Protein Details: P07437 (TUBB)

Protein Information
Accession P07437
Protein Names Tubulin beta chain (Tubulin beta-5 chain)
Gene Symbol TUBB; TUBB5; OK/SW-cl.56
Organism Homo sapiens (Human)
Length 444 aa
Isoforms No isoforms
Related PMIDs 21076176 29733200 31251020 32944167 36430497 37611173
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.562
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.562
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.156
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.094
6/25 (24.0%)
4
PC3 cells
Specificity: 0.062
4/4 (100.0%)
4
293T cells
Specificity: 0.062
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.062
4/4 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREIVHIQAG11QCGNQIGAKF21WEVISDEHGI31DPTGTYHGDS41DLQLDRISVY
51-10051YNEATGGKYV61PRAILVDLEP71GTMDSVRSGP81FGQIFRPDNF91VFGQSGAGNN
101-150101WAKGHYTEGA111ELVDSVLDVV121RKEAESCDCL131QGFQLTHSLG141GGTGSGMGTL
151-200151LISKIREEYP161DRIMNTFSVV171PSPKVSDTVV181EPYNATLSVH191QLVENTDETY
201-250201CIDNEALYDI211CFRTLKLTTP221TYGDLNHLVS231ATMSGVTTCL241RFPGQLNADL
251-300251RKLAVNMVPF261PRLHFFMPGF271APLTSRGSQQ281YRALTVPELT291QQVFDAKNMM
301-350301AACDPRHGRY311LTVAAVFRGR321MSMKEVDEQM331LNVQNKNSSY341FVEWIPNNVK
351-400351TAVCDIPPRG361LKMAVTFIGN371STAIQELFKR381ISEQFTAMFR391RKAFLHWYTG
401-444401EGMDEMEFTE411AESNMNDLVS421EYQQYQDATA431EEEEDFGEEA441EEEA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
127 Prediction (Low) - -
211 Prediction (Medium) - -
239 Prediction (High) - -
303 Prediction (High) - -
354 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Tubulin C-terminal domain 37611173
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
233 M → Cfs*14 0.002976 DEL Frame Shift Del KIRC
251 R → C 0.001887 SNP Missense Mutation UCEC