Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P07550 | ADRB2; ADRB2R; B2AR | Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) … | Homo sapiens (Human) | 413 aa |
Protein Details: P07550 (ADRB2)
Protein Information
| Accession | P07550 |
|---|---|
| Protein Names | Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) |
| Gene Symbol | ADRB2; ADRB2R; B2AR |
| Organism | Homo sapiens (Human) |
| Length | 413 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 37611173 |
| Database Sources | dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.893
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.893
25/46 (54.3%)
3
PC3 cells
Specificity: 0.107
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGQPGNGSAF11LLAPNGSHAP21DHDVTQERDE31VWVVGMGIVM41SLIVLAIVFG
51-10051NVLVITAIAK61FERLQTVTNY71FITSLACADL81VMGLAVVPFG91AAHILMKMWT
101-150101FGNFWCEFWT111SIDVLCVTAS121IETLCVIAVD131RYFAITSPFK141YQSLLTKNKA
151-200151RVIILMVWIV161SGLTSFLPIQ171MHWYRATHQE181AINCYANETC191CDFFTNQAYA
201-250201IASSIVSFYV211PLVIMVFVYS221RVFQEAKRQL231QKIDKSEGRF241HVQNLSQVEQ
251-300251DGRTGHGLRR261SSKFCLKEHK271ALKTLGIIMG281TFTLCWLPFF291IVNIVHVIQD
301-350301NLIRKEVYIL311LNWIGYVNSG321FNPLIYCRSP331DFRIAFQELL341CLRRSSLKAY
351-400351GNGYSSNGNT361GEQSGYHVEQ371EKENKLLCED381LPGTEDFVGH391QGTVPSDNID
401-413401SQGRNCSTND411SLL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 265 | DBPTM SWISSPALM Prediction (High) | - | - |
| 285 | Prediction (Low) | - | - |
| 341 | Experimental DBPTM SWISSPALM Prediction (High) | - | 37611173 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 49 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 91 | A → Cfs*23 | 0.003460 | INS | Frame Shift Ins | CESC |
| 106 | C → C | 0.001887 | SNP | Silent | UCEC |
| 184 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 185 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 304 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 343 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 343 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 343 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 190* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |