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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P07737 PFN1 Profilin-1 (Epididymis tissue protein Li … Homo sapiens (Human) 140 aa

Protein Details: P07737 (PFN1)

Protein Information
Accession P07737
Protein Names Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene Symbol PFN1
Organism Homo sapiens (Human)
Length 140 aa
Isoforms No isoforms
Related PMIDs 21076176 22496122 25914232 29575903 29733200 31251020 31382980 32944167 33636221 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.429
24/46 (52.2%)
10
HAP1 cells
Specificity: 0.179
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.071
4/25 (16.0%)
4
PC3 cells
Specificity: 0.071
4/4 (100.0%)
4
293T cells
Specificity: 0.071
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.071
4/4 (100.0%)
3
CEMx174 cells
Specificity: 0.054
3/3 (100.0%)
1
U937 cells
Specificity: 0.018
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.018
1/2 (50.0%)
1
Liver membrane
Specificity: 0.018
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAGWNAYIDN11LMADGTCQDA21AIVGYKDSPS31VWAAVPGKTF41VNITPAEVGV
51-10051LVGKDRSSFY61VNGLTLGGQK71CSVIRDSLLQ81DGEFSMDLRT91KSTGGAPTFN
101-140101VTVTKTDKTL111VLLMGKEGVH121GGLINKKCYE131MASHLRRSQY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
71 Prediction (Low) - -
128 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) - 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
17 C → _D27del 0.002288 DEL In Frame Del STAD
? ? → ? 0.002427 SNP Missense Mutation BLCA