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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P08100 RHO Rhodopsin (Opsin-2) Homo sapiens (Human) 348 aa

Protein Details: P08100 (RHO)

Protein Information
AccessionP08100
Protein NamesRhodopsin (Opsin-2)
Gene SymbolRHO
OrganismHomo sapiens (Human)
Length348 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNGTEGPNFY11VPFSNATGVV21RSPFEYPQYY31LAEPWQFSML41AAYMFLLIVL
51-10051GFPINFLTLY61VTVQHKKLRT71PLNYILLNLA81VADLFMVLGG91FTSTLYTSLH
101-150101GYFVFGPTGC111NLEGFFATLG121GEIALWSLVV131LAIERYVVVC141KPMSNFRFGE
151-200151NHAIMGVAFT161WVMALACAAP171PLAGWSRYIP181EGLQCSCGID191YYTLKPEVNN
201-250201ESFVIYMFVV211HFTIPMIIIF221FCYGQLVFTV231KEAAAQQQES241ATTQKAEKEV
251-300251TRMVIIMVIA261FLICWVPYAS271VAFYIFTHQG281SNFGPIFMTI291PAFFAKSAAI
301-348301YNPVIYIMMN311KQFRNCMLTT321ICCGKNPLGD331DEASATVSKT341ETSQVAPA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
110 - - -
Deep-Palm: 0.86
140 - - -
GPS-Palm: 0.92
Deep-Palm: 0.67
167 - - -
GPS-Palm: 0.78
Deep-Palm: 0.84
185 - - -
Deep-Palm: 0.69
187 - - -
GPS-Palm: 0.73
Deep-Palm: 0.57
222 - - -
GPS-Palm: 0.81
Deep-Palm: 0.11
264 - - -
Deep-Palm: 0.08
316 - - -
GPS-Palm: 0.90
Deep-Palm: 0.07
322 DBPTM SWISSPALM - - -
GPS-Palm: 0.92
Deep-Palm: 0.33
323 DBPTM SWISSPALM - - -
GPS-Palm: 0.92
Deep-Palm: 0.31
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
69 R → C 0.002288 SNP Missense Mutation STAD
69 R → C 0.001887 SNP Missense Mutation UCEC
89 G → C 0.001887 SNP Missense Mutation UCEC
167 C → C 0.002545 SNP Silent GBM
281 S → C 0.002427 SNP Missense Mutation BLCA
323 C → C 0.002506 SNP Silent COAD
323 C → C 0.003460 SNP Silent CESC
343 S → C 0.002288 SNP Missense Mutation STAD