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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P08134 RHOC; ARH9; ARHC Rho-related GTP-binding protein RhoC (Rho … Homo sapiens (Human) 193 aa

Protein Details: P08134 (RHOC)

Protein Information
Accession P08134
Protein Names Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene Symbol RHOC; ARH9; ARHC
Organism Homo sapiens (Human)
Length 193 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
2
DU145 cells
Specificity: 0.071
2/2 (100.0%)
2
PC3 cells
Specificity: 0.071
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAIRKKLVI11VGDGACGKTC21LLIVFSKDQF31PEVYVPTVFE41NYIADIEVDG
51-10051KQVELALWDT61AGQEDYDRLR71PLSYPDTDVI81LMCFSIDSPD91SLENIPEKWT
101-150101PEVKHFCPNV111PIILVGNKKD121LRQDEHTRRE131LAKMKQEPVR141SEEGRDMANR
151-193151ISAFGYLECS161AKTKEGVREV171FEMATRAGLQ181VRKNKRRRGC191PIL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
16 CYSMODDB SWISSPALM DBPTM Prediction (High) Ras family -
20 Prediction (Low) - -
107 CYSMODDB SWISSPALM DBPTM Ras family -
159 Prediction (High) - -
190 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
20 C → Ffs*86 0.001969 INS Frame Shift Ins HNSC
20 C → C 0.001887 SNP Silent UCEC
42 Y → C 0.001014 SNP Missense Mutation BRCA
189 G → C 0.002294 SNP Missense Mutation OV