Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P08174 | CD55 | Complement decay-accelerating factor (CD antigen … | Homo sapiens (Human) | 381 aa |
Protein Details: P08174 (CD55)
Protein Information
| Accession | P08174 |
|---|---|
| Protein Names | Complement decay-accelerating factor (CD antigen CD55) |
| Gene Symbol | CD55 |
| Organism | Homo sapiens (Human) |
| Length | 381 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTVARPSVPA11ALPLLGELPR21LLLLVLLCLP31AVWGDCGLPP41DVPNAQPALE
51-10051GRTSFPEDTV61ITYKCEESFV71KIPGEKDSVI81CLKGSQWSDI91EEFCNRSCEV
101-150101PTRLNSASLK111QPYITQNYFP121VGTVVEYECR131PGYRREPSLS141PKLTCLQNLK
151-200151WSTAVEFCKK161KSCPNPGEIR171NGQIDVPGGI181LFGATISFSC191NTGYKLFGST
201-250201SSFCLISGSS211VQWSDPLPEC221REIYCPAPPQ231IDNGIIQGER241DHYGYRQSVT
251-300251YACNKGFTMI261GEHSIYCTVN271NDEGEWSGPP281PECRGKSLTS291KVPPTVQKPT
301-350301TVNVPTTEVS311PTSQKTTTKT321TTPNAQATRS331TPVSRTTKHF341HETTPNKGSG
351-381351TTSGTTRLLS361GHTCFTLTGL371LGTLVTMGLL381T
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 28 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.98
|
|
| 36 | - | - | - |
Deep-Palm: 0.98
|
|
| 65 | - | - | - |
Deep-Palm: 0.68
|
|
| 81 | - | - | - |
Deep-Palm: 0.60
|
|
| 94 | - | - | - |
Deep-Palm: 0.80
|
|
| 98 | - | - | - |
Deep-Palm: 0.74
|
|
| 129 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.54
|
|
| 145 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.93
|
|
| 158 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.24
|
|
| 163 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.41
|
|
| 190 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.32
|
|
| 204 | - | - | - |
Deep-Palm: 0.39
|
|
| 220 | - | - | - |
Deep-Palm: 0.27
|
|
| 225 | - | - | - |
Deep-Palm: 0.44
|
|
| 253 | - | - | - |
Deep-Palm: 0.05
|
|
| 267 | - | - | - |
Deep-Palm: 0.06
|
|
| 283 | - | - | - |
Deep-Palm: 0.61
|
|
| 364 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
CEM 174 cell
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 127 | Y → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 129 | C → R | 0.002506 | SNP | Missense Mutation | COAD |
| 264 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 267 | C → F | 0.002545 | SNP | Missense Mutation | GBM |