Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P08195-2 | SLC3A2 | Amino acid transporter heavy chain … | Homo sapiens (Human) | 529 aa |
Protein Details: P08195-2 (SLC3A2)
Protein Information
| Accession | P08195-2 |
|---|---|
| Protein Names | Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98) |
| Gene Symbol | SLC3A2 |
| Organism | Homo sapiens (Human) |
| Length | 529 aa |
| Isoforms | |
| Related PMIDs | 31251020 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSQDTEVDMK11EVELNELEPE21KQPMNAASGA31AMSLAGAEKN41GLVKIKVAED
51-10051EAEAAAAAKF61TGLSKEELLK71VAGSPGWVRT81RWALLLLFWL91GWLGMLAGAV
101-150101VIIVRAPRCR111ELPAQKWWHT121GALYRIGDLQ131AFQGHGAGNL141AGLKGRLDYL
151-200151SSLKVKGLVL161GPIHKNQKDD171VAQTDLLQID181PNFGSKEDFD191SLLQSAKKKS
201-250201IRVILDLTPN211YRGENSWFST221QVDTVATKVK231DALEFWLQAG241VDGFQVRDIE
251-300251NLKDASSFLA261EWQNITKGFS271EDRLLIAGTN281SSDLQQILSL291LESNKDLLLT
301-350301SSYLSDSGST311GEHTKSLVTQ321YLNATGNRWC331SWSLSQARLL341TSFLPAQLLR
351-400351LYQLMLFTLP361GTPVFSYGDE371IGLDAAALPG381QPMEAPVMLW391DESSFPDIPG
401-450401AVSANMTVKG411QSEDPGSLLS421LFRRLSDQRS431KERSLLHGDF441HAFSAGPGLF
451-500451SYIRHWDQNE461RFLVVLNFGD471VGLSAGLQAS481DLPASASLPA491KADLLLSTQP
501-529501GREEGSPLEL511ERLKLEPHEG521LLLRFPYAA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 43 | - | - | - |
Deep-Palm: 0.98
|
|
| 74 | - | - | - |
Deep-Palm: 0.91
|
|
| 210 | - | - | - |
Deep-Palm: 0.92
|
|
| 330 | - |
HeLa
(29575903)
| - | - | |
| 431 | - | - | - |
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
1
heart
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 430 | W → C | 0.002545 | SNP | Missense Mutation | GBM |
| 534 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 613 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |