Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P08249 | Mdh2 | Malate dehydrogenase, mitochondrial (EC 1.1.1.37) | Mus musculus (Mouse) | 338 aa |
Protein Details: P08249 (Mdh2)
Protein Information
| Accession | P08249 |
|---|---|
| Protein Names | Malate dehydrogenase, mitochondrial (EC 1.1.1.37) |
| Gene Symbol | Mdh2 |
| Organism | Mus musculus (Mouse) |
| Length | 338 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29217618 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLSALARPAG11AALRRSFSTS21AQNNAKVAVL31GASGGIGQPL41SLLLKNSPLV
51-10051SRLTLYDIAH61TPGVAADLSH71IETRANVKGY81LGPEQLPDCL91KGCDVVVIPA
101-150101GVPRKPGMTR111DDLFNTNATI121VATLTAACAQ131HCPEAMVCII141ANPVNSTIPI
151-200151TAEVFKKHGV161YNPNKIFGVT171TLDIVRANTF181VAELKGLDPA191RVNVPVIGGH
201-250201AGKTIIPLIS211QCTPKVDFPQ221DQLATLTGRI231QEAGTEVVKA241KAGAGSATLS
251-300251MAYAGARFVF261SLVDAMNGKE271GVVECSFVQS281KETECTYFST291PLLLGKKGLE
301-338301KNLGIGKITP311FEEKMIAEAI321PELKASIKKG331EDFVKNMK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 89 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase, NAD binding domain |
Brain
(31311849)
brain
(39008777)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.75
Deep-Palm: 0.97
|
| 93 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase, NAD binding domain |
Brain
(31311849)
brain
(39008777)
MLE
(39008777)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.69
Deep-Palm: 0.98
|
| 128 | - | - | - |
Deep-Palm: 0.40
|
|
| 132 | - | - | - |
Deep-Palm: 0.13
|
|
| 138 | - | - | - |
Deep-Palm: 0.11
|
|
| 212 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase alpha/beta C-terminal domain |
Brain
(31311849)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.92
Deep-Palm: 0.89
|
| 275 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase alpha/beta C-terminal domain |
Brain
(31311849)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.88
Deep-Palm: 0.51
|
| 285 | SWISSPALM DBPTM CYSMODDB | lactate/malate dehydrogenase alpha/beta C-terminal domain |
Liver
(28526873)
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
6
Liver
Specificity: 0.109
6/6 (100.0%)
5
Brain
Specificity: 0.091
5/5 (100.0%)
2
Testis
Specificity: 0.036
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.018
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
41
Brain tissue (Mass)
Specificity: 0.745
41/56 (73.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.