Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P08572 COL4A2 Collagen alpha-2(IV) chain [Cleaved into: … Homo sapiens (Human) 1712 aa

Protein Details: P08572 (COL4A2)

Protein Information
AccessionP08572
Protein NamesCollagen alpha-2(IV) chain [Cleaved into: Canstatin]
Gene SymbolCOL4A2
OrganismHomo sapiens (Human)
Length1712 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGRDQRAVAG11PALRRWLLLG21TVTVGFLAQS31VLAGVKKFDV41PCGGRDCSGG
51-10051CQCYPEKGGR61GQPGPVGPQG71YNGPPGLQGF81PGLQGRKGDK91GERGAPGVTG
101-150101PKGDVGARGV111SGFPGADGIP121GHPGQGGPRG131RPGYDGCNGT141QGDSGPQGPP
151-200151GSEGFTGPPG161PQGPKGQKGE171PYALPKEERD181RYRGEPGEPG191LVGFQGPPGR
201-250201PGHVGQMGPV211GAPGRPGPPG221PPGPKGQQGN231RGLGFYGVKG241EKGDVGQPGP
251-300251NGIPSDTLHP261IIAPTGVTFH271PDQYKGEKGS281EGEPGIRGIS291LKGEEGIMGF
301-350301PGLRGYPGLS311GEKGSPGQKG321SRGLDGYQGP331DGPRGPKGEA341GDPGPPGLPA
351-400351YSPHPSLAKG361ARGDPGFPGA371QGEPGSQGEP381GDPGLPGPPG391LSIGDGDQRR
401-450401GLPGEMGPKG411FIGDPGIPAL421YGGPPGPDGK431RGPPGPPGLP441GPPGPDGFLF
451-500451GLKGAKGRAG461FPGLPGSPGA471RGPKGWKGDA481GECRCTEGDE491AIKGLPGLPG
501-550501PKGFAGINGE511PGRKGDRGDP521GQHGLPGFPG531LKGVPGNIGA541PGPKGAKGDS
551-600551RTITTKGERG561QPGVPGVPGM571KGDDGSPGRD581GLDGFPGLPG591PPGDGIKGPP
601-650601GDPGYPGIPG611TKGTPGEMGP621PGLGLPGLKG631QRGFPGDAGL641PGPPGFLGPP
651-700651GPAGTPGQID661CDTDVKRAVG671GDRQEAIQPG681CIGGPKGLPG691LPGPPGPTGA
701-750701KGLRGIPGFA711GADGGPGPRG721LPGDAGREGF731PGPPGFIGPR741GSKGAVGLPG
751-800751PDGSPGPIGL761PGPDGPPGER771GLPGEVLGAQ781PGPRGDAGVP791GQPGLKGLPG
801-850801DRGPPGFRGS811QGMPGMPGLK821GQPGLPGPSG831QPGLYGPPGL841HGFPGAPGQE
851-900851GPLGLPGIPG861REGLPGDRGD871PGDTGAPGPV881GMKGLSGDRG891DAGFTGEQGH
901-950901PGSPGFKGID911GMPGTPGLKG921DRGSPGMDGF931QGMPGLKGRP941GFPGSKGEAG
951-1000951FFGIPGLKGL961AGEPGFKGSR971GDPGPPGPPP981VILPGMKDIK991GEKGDEGPMG
1001-10501001LKGYLGAKGI1011QGMPGIPGLS1021GIPGLPGRPG1031HIKGVKGDIG1041VPGIPGLPGF
1051-11001051PGVAGPPGIT1061GFPGFIGSRG1071DKGAPGRAGL1081YGEIGATGDF1091GDIGDTINLP
1101-11501101GRPGLKGERG1111TTGIPGLKGF1121FGEKGTEGDI1131GFPGITGVTG1141VQGPPGLKGQ
1151-12001151TGFPGLTGPP1161GSQGELGRIG1171LPGGKGDDGW1181PGAPGLPGFP1191GLRGIRGLHG
1201-12501201LPGTKGFPGS1211PGSDIHGDPG1221FPGPPGERGD1231PGEANTLPGP1241VGVPGQKGDQ
1251-13001251GAPGERGPPG1261SPGLQGFPGI1271TPPSNISGAP1281GDKGAPGIFG1291LKGYRGPPGP
1301-13501301PGSAALPGSK1311GDTGNPGAPG1321TPGTKGWAGD1331SGPQGRPGVF1341GLPGEKGPRG
1351-14001351EQGFMGNTGP1361TGAVGDRGPK1371GPKGDPGFPG1381APGTVGAPGI1391AGIPQKIAVQ
1401-14501401PGTVGPQGRR1411GPPGAPGEMG1421PQGPPGEPGF1431RGAPGKAGPQ1441GRGGVSAVPG
1451-15001451FRGDEGPIGH1461QGPIGQEGAP1471GRPGSPGLPG1481MPGRSVSIGY1491LLVKHSQTDQ
1501-15501501EPMCPVGMNK1511LWSGYSLLYF1521EGQEKAHNQD1531LGLAGSCLAR1541FSTMPFLYCN
1551-16001551PGDVCYYASR1561NDKSYWLSTT1571APLPMMPVAE1581DEIKPYISRC1591SVCEAPAIAI
1601-16501601AVHSQDVSIP1611HCPAGWRSLW1621IGYSFLMHTA1631AGDEGGGQSL1641VSPGSCLEDF
1651-17001651RATPFIECNG1661GRGTCHYYAN1671KYSFWLTTIP1681EQSFQGSPSA1691DTLKAGLIRT
1701-17121701HISRCQVCMK1711NL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
42 SWISSPALM DBPTM CYSMODDB - - -
Deep-Palm: 0.58
47 - - -
Deep-Palm: 0.52
51 - - -
Deep-Palm: 0.18
53 - - -
Deep-Palm: 0.20
137 - - -
Deep-Palm: 0.12
483 - - -
Deep-Palm: 0.70
485 - - -
Deep-Palm: 0.66
661 - - -
Deep-Palm: 0.89
681 - - -
GPS-Palm: 0.89
Deep-Palm: 0.93
1504 - - -
Deep-Palm: 0.12
1537 - - -
Deep-Palm: 0.83
1549 - - -
Deep-Palm: 0.63
1555 - - -
Deep-Palm: 0.16
1590 - - -
Deep-Palm: 0.68
1593 - - -
Deep-Palm: 0.83
1612 - - -
Deep-Palm: 0.16
1646 - - -
Deep-Palm: 0.94
1658 - - -
GPS-Palm: 0.71
Deep-Palm: 0.21
1665 - - -
Deep-Palm: 0.08
1705 - - -
GPS-Palm: 0.78
Deep-Palm: 0.02
1708 - - -
GPS-Palm: 0.94
Deep-Palm: 0.01
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
200 R → C 0.002288 SNP Missense Mutation STAD
308 G → C 0.002033 SNP Missense Mutation LUSC
485 C → R 0.002033 SNP Missense Mutation LUSC
579 R → C 0.002288 SNP Missense Mutation STAD
590 G → C 0.002033 SNP Missense Mutation LUSC
630 G → C 0.002288 SNP Missense Mutation STAD
632 R → C 0.001969 SNP Missense Mutation HNSC
696 G → C 0.001764 SNP Missense Mutation LUAD
833 G → C 0.005618 SNP Missense Mutation PAAD
861 R → C 0.002033 SNP Missense Mutation LUSC
932 G → C 0.001887 SNP Missense Mutation UCEC
1030 G → C 0.001014 SNP Missense Mutation BRCA
1030 G → C 0.002033 SNP Missense Mutation LUSC
1431 R → C 0.001887 SNP Missense Mutation UCEC
1651 R → C 0.002427 SNP Missense Mutation BLCA
1651 R → C 0.002545 SNP Missense Mutation GBM
1699 R → C 0.002141 SNP Missense Mutation SKCM