Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P08574 | CYC1 | Cytochrome c1, heme protein, mitochondrial … | Homo sapiens (Human) | 325 aa |
Protein Details: P08574 (CYC1)
Protein Information
| Accession | P08574 |
|---|---|
| Protein Names | Cytochrome c1, heme protein, mitochondrial (EC 7.1.1.8) (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1) |
| Gene Symbol | CYC1 |
| Organism | Homo sapiens (Human) |
| Length | 325 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 31382980 32944167 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.706
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.706
36/46 (78.3%)
6
293T cells
Specificity: 0.118
6/10 (60.0%)
4
HAP1 cells
Specificity: 0.078
4/10 (40.0%)
2
PC3 cells
Specificity: 0.039
2/4 (50.0%)
1
U937 cells
Specificity: 0.020
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.020
1/2 (50.0%)
1
Liver membrane
Specificity: 0.020
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAAAASLRG11VVLGPRGAGL21PGARARGLLC31SARPGQLPLR41TPQAVALSSK
51-10051SGLSRGRKVM61LSALGMLAAG71GAGLAMALHS81AVSASDLELH91PPSYPWSHRG
101-150101LLSSLDHTSI111RRGFQVYKQV121CASCHSMDFV131AYRHLVGVCY141TEDEAKELAA
151-200151EVEVQDGPNE161DGEMFMRPGK171LFDYFPKPYP181NSEAARAANN191GALPPDLSYI
201-250201VRARHGGEDY211VFSLLTGYCE221PPTGVSLREG231LYFNPYFPGQ241AIAMAPPIYT
251-300251DVLEFDDGTP261ATMSQIAKDV271CTFLRWASEP281EHDHRKRMGL291KMLMMMALLV
301-325301PLVYTIKRHK311WSVLKSRKLA321YRPPK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 30 | Prediction (High) | - | - |
| 139 | Prediction (High) | - | - |
| 219 | Prediction (Low) | - | - |
| 271 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 54 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 121 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 255 | F → C | 0.002288 | SNP | Missense Mutation | STAD |
| 287 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |