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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P08588 ADRB1 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) … Homo sapiens (Human) 477 aa

Protein Details: P08588 (ADRB1)

Protein Information
AccessionP08588
Protein NamesBeta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)
Gene SymbolADRB1
OrganismHomo sapiens (Human)
Length477 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGAGVLVLGA11SEPGNLSSAA21PLPDGAATAA31RLLVPASPPA41SLLPPASESP
51-10051EPLSQQWTAG61MGLLMALIVL71LIVAGNVLVI81VAIAKTPRLQ91TLTNLFIMSL
101-150101ASADLVMGLL111VVPFGATIVV121WGRWEYGSFF131CELWTSVDVL141CVTASIETLC
151-200151VIALDRYLAI161TSPFRYQSLL171TRARARGLVC181TVWAISALVS191FLPILMHWWR
201-250201AESDEARRCY211NDPKCCDFVT221NRAYAIASSV231VSFYVPLCIM241AFVYLRVFRE
251-300251AQKQVKKIDS261CERRFLGGPA271RPPSPSPSPV281PAPAPPPGPP291RPAAAAATAP
301-350301LANGRAGKRR311PSRLVALREQ321KALKTLGIIM331GVFTLCWLPF341FLANVVKAFH
351-400351RELVPDRLFV361FFNWLGYANS371AFNPIIYCRS381PDFRKAFQGL391LCCARRAARR
401-450401RHATHGDRPR411ASGCLARPGP421PPSPGAASDD431DDDDVVGATP441PARLLEPWAG
451-477451CNGGAAADSD461SSLDEPCRPG471FASESKV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
131 - - -
Deep-Palm: 0.27
141 - - -
Deep-Palm: 0.14
150 - - -
Deep-Palm: 0.71
180 - - -
GPS-Palm: 0.88
Deep-Palm: 0.97
209 - - -
Deep-Palm: 0.04
215 - - -
Deep-Palm: 0.20
216 - - -
GPS-Palm: 0.75
Deep-Palm: 0.19
238 - - -
Deep-Palm: 0.75
261 - - -
GPS-Palm: 0.86
Deep-Palm: 0.94
336 - - -
Deep-Palm: 0.72
378 - - -
GPS-Palm: 0.80
Deep-Palm: 0.09
392 DBPTM SWISSPALM - - -
GPS-Palm: 0.97
Deep-Palm: 0.88
393 DBPTM SWISSPALM - - -
GPS-Palm: 0.97
Deep-Palm: 0.89
414 DBPTM SWISSPALM - - -
GPS-Palm: 0.74
Deep-Palm: 0.93
451 - - -
GPS-Palm: 0.83
Deep-Palm: 0.97
467 - - -
Deep-Palm: 0.12
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
131 C → S 0.001887 SNP Missense Mutation UCEC
156 R → C 0.007299 SNP Missense Mutation READ
249 R → C 0.002288 SNP Missense Mutation STAD
249 R → C 0.001969 SNP Missense Mutation HNSC
263 R → C 0.001887 SNP Missense Mutation UCEC