Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P08752 | Gnai2 | Guanine nucleotide-binding protein G(i) subunit … | Mus musculus (Mouse) | 355 aa |
Protein Details: P08752 (Gnai2)
Protein Information
| Accession | P08752 |
|---|---|
| Protein Names | Guanine nucleotide-binding protein G(i) subunit alpha-2 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein) |
| Gene Symbol | Gnai2 |
| Organism | Mus musculus (Mouse) |
| Length | 355 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29217618 29575903 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCTVSAEDK11AAAERSKMID21KNLREDGEKA31AREVKLLLLG41AGESGKSTIV
51-10051KQMKIIHEDG61YSEEECRQYR71AVVYSNTIQS81IMAIVKAMGN91LQIDFADPQR
101-150101ADDARQLFAL111SCAAEEQGML121PEDLSGVIRR131LWADHGVQAC141FGRSREYQLN
151-200151DSAAYYLNDL161ERIAQSDYIP171TQQDVLRTRV181KTTGIVETHF191TFKDLHFKMF
201-250201DVGGQRSERK211KWIHCFEGVT221AIIFCVALSA231YDLVLAEDEE241MNRMHESMKL
251-300251FDSICNNKWF261TDTSIILFLN271KKDLFEEKIT281QSSLTICFPE291YTGANKYDEA
301-350301ASYIQSKFED311LNKRKDTKEI321YTHFTCATDT331KNVQFVFDAV341TDVIIKNNLK
351-355351DCGLF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.04
|
|
| 66 | G-protein alpha subunit |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.14
|
|
| 112 | - |
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.72
Deep-Palm: 0.96
|
|
| 140 | SWISSPALM DBPTM CYSMODDB | G-protein alpha subunit |
Brain
(31311849)
Forebrain
(28680068)
brain
(39008777)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.73
Deep-Palm: 0.89
|
| 215 | - | - | - |
Deep-Palm: 0.80
|
|
| 225 | - | - | - |
Deep-Palm: 0.70
|
|
| 255 | SWISSPALM DBPTM CYSMODDB | G-protein alpha subunit |
Brain
(31311849)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.32
|
| 287 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.86
Deep-Palm: 0.80
|
|
| 326 | G-protein alpha subunit |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.28
|
|
| 352 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.353
6
Liver
Specificity: 0.128
6/6 (100.0%)
5
Brain
Specificity: 0.106
5/5 (100.0%)
4
Raw 264.7
Specificity: 0.085
4/4 (100.0%)
2
Testis
Specificity: 0.043
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.933
28
Brain tissue (Mass)
Specificity: 0.596
28/56 (50.0%)
2
Liver tissue (Mass)
Specificity: 0.043
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.