Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P08865 | RPSA | Small ribosomal subunit protein uS2 … | Homo sapiens (Human) | 295 aa |
Protein Details: P08865 (RPSA)
Protein Information
| Accession | P08865 |
|---|---|
| Protein Names | Small ribosomal subunit protein uS2 (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4) |
| Gene Symbol | RPSA |
| Organism | Homo sapiens (Human) |
| Length | 295 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGALDVLQM11KEEDVLKFLA21AGTHLGGTNL31DFQMEQYIYK41RKSDGIYIIN
51-10051LKRTWEKLLL61AARAIVAIEN71PADVSVISSR81NTGQRAVLKF91AAATGATPIA
101-150101GRFTPGTFTN111QIQAAFREPR121LLVVTDPRAD131HQPLTEASYV141NLPTIALCNT
151-200151DSPLRYVDIA161IPCNNKGAHS171VGLMWWMLAR181EVLRMRGTIS191REHPWEVMPD
201-250201LYFYRDPEEI211EKEEQAAAEK221AVTKEEFQGE231WTAPAPEFTA241TQPEVADWSE
251-295251GVQVPSVPIQ261QFPTEDWSAQ271PATEDWSAAP281TAQATEWVGA291TTDWS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 148 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein S2 |
HeLa
(29575903)
|
Unknown
(32651440)
|
GPS-Palm: 0.87
Deep-Palm: 0.97
|
| 163 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein S2 |
HeLa
(37611173)
| - |
GPS-Palm: 0.86
Deep-Palm: 0.43
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.333
2/2 (100.0%)
1
293T cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 191 | R → C | 0.002288 | SNP | Missense Mutation | STAD |