Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P09103 | P4hb | Protein disulfide-isomerase (PDI) (EC 5.3.4.1) … | Mus musculus (Mouse) | 509 aa |
Protein Details: P09103 (P4hb)
Protein Information
| Accession | P09103 |
|---|---|
| Protein Names | Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Endoplasmic reticulum resident protein 59) (ER protein 59) (ERp59) (Prolyl 4-hydroxylase subunit beta) (p55) |
| Gene Symbol | P4hb |
| Organism | Mus musculus (Mouse) |
| Length | 509 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLSRALLCLA11LAWAARVGAD21ALEEEDNVLV31LKKSNFEEAL41AAHKYLLVEF
51-10051YAPWCGHCKA61LAPEYAKAAA71KLKAEGSEIR81LAKVDATEES91DLAQQYGVRG
101-150101YPTIKFFKNG111DTASPKEYTA121GREADDIVNW131LKKRTGPAAT141TLSDTAAAES
151-200151LVDSSEVTVI161GFFKDVESDS171AKQFLLAAEA181IDDIPFGITS191NSGVFSKYQL
201-250201DKDGVVLFKK211FDEGRNNFEG221EITKEKLLDF231IKHNQLPLVI241EFTEQTAPKI
251-300251FGGEIKTHIL261LFLPKSVSDY271DGKLSSFKRA281AEGFKGKILF291IFIDSDHTDN
301-350301QRILEFFGLK311KEECPAVRLI321TLEEEMTKYK331PESDELTAEK341ITEFCHRFLE
351-400351GKIKPHLMSQ361EVPEDWDKQP371VKVLVGANFE381EVAFDEKKNV391FVEFYAPWCG
401-450401HCKQLAPIWD411KLGETYKDHE421NIIIAKMDST431ANEVEAVKVH441SFPTLKFFPA
451-500451SADRTVIDYN461GERTLDGFKK471FLESGGQDGA481GDDEDLDLEE491ALEPDMEEDD
501-509501DQKAVKDEL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.52
|
|
| 55 | - | - | - |
Deep-Palm: 0.84
|
|
| 58 | - | - | - |
Deep-Palm: 0.92
|
|
| 314 | SWISSPALM DBPTM CYSMODDB | Thioredoxin-like domain |
liver
(26165157)
| - |
GPS-Palm: 0.84
Deep-Palm: 0.97
|
| 345 | SWISSPALM DBPTM CYSMODDB | - |
liver
(26165157)
|
Brain
(35358180)
|
GPS-Palm: 0.86
Deep-Palm: 0.89
|
| 399 | - | - | - |
Deep-Palm: 0.18
|
|
| 402 | - | - | - |
Deep-Palm: 0.18
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Liver
Specificity: 0.208
5/5 (100.0%)
2
Brain
Specificity: 0.083
2/2 (100.0%)
2
Testis
Specificity: 0.083
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.625
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.