Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P09110-2 | ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) … | Homo sapiens (Human) | 331 aa |
Protein Details: P09110-2 (ACAA1)
Protein Information
| Accession | P09110-2 |
|---|---|
| Protein Names | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) |
| Gene Symbol | ACAA1 |
| Organism | Homo sapiens (Human) |
| Length | 331 aa |
| Isoforms | |
| Related PMIDs | 31251020 32651440 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MQRLQVVLGH11LRGPADSGWM21PQAAPCLSGA31PQASAADVVV41VHGRRTAICR
51-10051AGRGGFKDTT61PDELLSAVMT71AVLKDVNLRP81EQLGDICVGN91VLQPGAGAIM
101-150101ARIAQFLSDI111PETVPLSTVN121RQCSSGLQAV131ASIAGGIRNG141SYDIGMACGI
151-200151TSENVAERFG161ISREKQDTFA171LASQQKAARA181QSKGCFQAEI191VPVTTTVHDD
201-250201KGTKRSITVT211QDEGIRPSTT221MEGLAKLKPA231FKKDGSTTAG241LTVSDVDIFE
251-300251INEAFASQAA261YCVEKLRLPP271EKVNPLGGAV281ALGHPLGCTG291ARQVITLLNE
301-331301LKRRGKRAYG311VVSMCIGTGM321GAAAVFEYPG331N
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 26 | - | - | - |
Deep-Palm: 0.91
|
|
| 49 | Thiolase-like Thiolase-like superfamily, Thiolase | - | - |
Deep-Palm: 0.90
|
|
| 87 | - | - | - |
Deep-Palm: 0.98
|
|
| 123 | - | - | - |
Deep-Palm: 0.97
|
|
| 148 | - | - | - |
Deep-Palm: 0.76
|
|
| 177 | - | - | - |
Deep-Palm: 0.93
|
|
| 218 | - | - | - |
Deep-Palm: 0.85
|
|
| 288 | - | - | - |
GPS-Palm: 0.90
|
|
| 355 | - | - | - |
Deep-Palm: 0.97
|
|
| 381 | - | - | - |
Deep-Palm: 0.98
|
|
| 408 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
LNCaP
Specificity: 0.667
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 123 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 396 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |